H R Valentine
Overview
Explore the profile of H R Valentine including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
209
Followers
0
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Recent Articles
1.
Hunter B, Eustace A, Irlam J, Valentine H, Denley H, Oguejiofor K, et al.
Br J Cancer
. 2014 Jun;
111(3):437-43.
PMID: 24937673
Background: The addition of carbogen and nicotinamide (CON) to radiotherapy (RT) improves overall survival in invasive bladder cancer. We explored whether expression of the hypoxia marker hypoxia-inducible factor-1α (HIF-1α) alone...
2.
Douglas C, Bernstein J, Ormston V, Hall R, Merve A, Swindell R, et al.
Clin Oncol (R Coll Radiol)
. 2012 Jul;
25(1):59-65.
PMID: 22841149
Aims: To evaluate the prognostic significance of potential tumour markers of hypoxia and apoptosis in early squamous cell carcinoma of the glottic larynx managed with radiotherapy. Materials And Methods: In...
3.
Hall J, Taylor J, Valentine H, Irlam J, Eustace A, Hoskin P, et al.
Br J Cancer
. 2012 Jul;
107(4):684-94.
PMID: 22805332
Background: As degradation of formalin-fixed paraffin-embedded (FFPE) samples limits the ability to profile mRNA expression, we explored factors predicting the success of mRNA expression profiling of FFPE material and investigated...
4.
Hall J, Leong H, Armenoult L, Newton G, Valentine H, Irlam J, et al.
Br J Cancer
. 2011 Mar;
104(6):971-81.
PMID: 21407225
Background: Degradation and chemical modification of RNA in formalin-fixed paraffin-embedded (FFPE) samples hamper their use in expression profiling studies. This study aimed to show that useful information can be obtained...
5.
Griffiths E, Pritchard S, McGrath S, Valentine H, Price P, Welch I, et al.
Br J Cancer
. 2008 Feb;
98(5):965-73.
PMID: 18283323
The study investigated hypoxia-associated markers (HIF-2alpha, Epo, Epo-R, Glut-1 and VEGF) along with Ki-67 in a gastric carcinogenesis model, and the prognostic significance of hypoxia-inducible factor (HIF)-2alpha in surgically treated...
6.
Griffiths E, Pritchard S, McGrath S, Valentine H, Price P, Welch I, et al.
Br J Cancer
. 2007 Apr;
96(9):1377-83.
PMID: 17437013
Hypoxia-associated markers are involved in the progression of several malignancies, but are relatively unstudied in Barrett's carcinogenesis. Our aim was to assess the immunohistochemical expression of hypoxia-inducible factor (HIF)-1alpha, HIF-2alpha,...
7.
Griffiths E, Pritchard S, Valentine H, Whitchelo N, Bishop P, Ebert M, et al.
Br J Cancer
. 2006 Dec;
96(1):95-103.
PMID: 17179985
Hypoxia-inducible factor-1 (HIF-1)alpha expression was studied in the gastric carcinogenesis sequence and as a prognostic factor in surgically resected gastric and gastro-oesophageal junction tumours. Protein expression was examined using immunohistochemistry...
8.
Green M, Hutchison G, Valentine H, Fitzmaurice R, Davidson S, Hunter R, et al.
Br J Cancer
. 2005 Feb;
92(3):449-58.
PMID: 15685241
The Bcl-2 family of apoptotic regulators is thought to play an essential role in cancer development and influence the sensitivity of tumour cells to radiotherapy. Bid is an abundantly expressed...