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H P Bryer

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Citations 53
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Recent Articles
1.
Goodman G, Dissanayake I, Bowman A, Pun S, Ma Y, Jee W, et al.
Bone . 2001 Jun; 28(6):583-8. PMID: 11425645
Cyclosporine A (CsA), a potent immunosuppressant used in transplantation, induces increased formation with excess resorption in the rat with resultant osteopenia. These findings are confirmed in the human model. Transforming...
2.
Sass D, Rucinski B, Bryer H, MANN G, Yuan Z, Ma Y, et al.
Bone . 1996 Oct; 19(4):381-6. PMID: 8894144
Cyclosporine (CsA) is a potent immunosuppressant that has revolutionized the success of organ transplantation. Flurbiprofen (FB), a propionic acid derivative NSAID, has been demonstrated in vivo to reduce osteoclast numbers...
3.
MANN G, Sass D, Chen H, Buchinsky F, Bryer H, Ma Y, et al.
Calcif Tissue Int . 1996 Jul; 59(1):38-44. PMID: 8661983
Immunosuppression with cyclosporin A (CsA) is effective in a number of immune-mediated diseases and in preventing rejection following organ transplantation. We have repeatedly demonstrated that CsA in the rat model...
4.
Buchinsky F, Ma Y, MANN G, Rucinski B, Bryer H, Romero D, et al.
Endocrinology . 1996 Jun; 137(6):2278-85. PMID: 8641176
The T lymphocyte suppressor, cyclosporin A, has been shown to cause high turnover osteoporosis. We postulated that cyclosporin A may exert its effects via the T cell rather than direct...
5.
Buchinsky F, Ma Y, MANN G, Rucinski B, Bryer H, Paynton B, et al.
J Bone Miner Res . 1995 Oct; 10(10):1556-65. PMID: 8686513
The immune and skeletal systems are known to interact. We have repeatedly shown that in contrast to in vitro data, the administration of T lymphocyte immunosuppressants, such as cyclosporin A,...
6.
Romero D, Buchinsky F, Rucinski B, Cvetkovic M, Bryer H, Liang X, et al.
J Bone Miner Res . 1995 May; 10(5):760-8. PMID: 7543725
Immunosuppressant therpay is associated with osteoporosis both clinically, post-transplantation, and experimentally. In rats, cyclosporin A (CsA) and FK506 induce a state of high turnover rapid bone loss. After 14 days...
7.
Romero D, Bryer H, Rucinski B, Isserow J, Buchinsky F, Cvetkovic M, et al.
Calcif Tissue Int . 1995 Jan; 56(1):54-61. PMID: 7796348
Amylin is normally secreted in a regulated fashion by the pancreatic beta-cells in parallel with insulin and has been reported to have bone-conserving properties. Type I diabetes mellitus results in...
8.
Bryer H, Isserow J, ARMSTRONG E, MANN G, Rucinski B, Buchinsky F, et al.
J Bone Miner Res . 1995 Jan; 10(1):132-8. PMID: 7747620
The immunosuppressant agent cyclosporin A (CsA) induces a high turnover osteopenic state, while the effect on bone of the antimetabolite azathioprine, a drug often used in conjunction with CsA in...