H Lentzen
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Explore the profile of H Lentzen including associated specialties, affiliations and a list of published articles.
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41
Citations
245
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Recent Articles
1.
Hajto T, Hostanska K, Fischer J, Lentzen H
Phytomedicine
. 2012 Dec;
3(2):129-37.
PMID: 23194960
Injections of non-toxic doses of purified galactoside-specific lectin from the Viscum album plant (VAA-I) caused significant changes in the cellular host defense system in animal models. To establish the immunomodulatory...
2.
Schoffski P, Breidenbach I, Krauter J, Bolte O, Stadler M, Ganser A, et al.
Eur J Cancer
. 2005 May;
41(10):1431-8.
PMID: 15913988
Aviscumine is a ribosome-inactivating protein with potent antitumour activity in vitro and in vivo and is an Escherichia coli-derived recombinant counterpart of natural mistletoe lectin-I. The current study was performed...
3.
Schoffski P, Riggert S, Fumoleau P, Campone M, Bolte O, Marreaud S, et al.
Ann Oncol
. 2004 Nov;
15(12):1816-24.
PMID: 15550588
Background: Aviscumine is an Escherichia coli-derived recombinant type II ribosome-inactivating protein with potent antitumor activity in vitro and in vivo. It is the recombinant counterpart of natural mistletoe lectin-I. The...
4.
Schaffrath B, Mengs U, Schwarz T, Hilgers R, Beuth J, Mockel B, et al.
Anticancer Res
. 2002 Mar;
21(6A):3981-7.
PMID: 11911280
The antitumoral and immunostimulating properties of rViscumin (recombinant mistletoe lectin) were investigated in two mouse tumor models. After intravenous inoculation with RAW-117-P or L-1 sarcoma cells in Balb/c mice, rViscumin...
5.
Hostanska K, Hajto T, Fischer J, Mengs U, Weber K, Lentzen H, et al.
Cancer Detect Prev
. 1999 Nov;
23(6):511-23.
PMID: 10571662
Growing evidence suggests that lectin-carbohydrate interactions are involved in the regulation of the balance between cell growth and programmed cell death. Viscum album agglutinin (VAA)-I is a galactoside-specific, type II...
6.
Langer M, Mockel B, Eck J, Zinke H, Lentzen H
Biochem Biophys Res Commun
. 1999 Nov;
264(3):944-8.
PMID: 10544035
Recombinant mistletoe lectin (rML) belongs to the class of type II ribosome-inactivating proteins (RIP) composed of a catalytically active A-chain with rRNA N-glycosidase activity and a B-chain with carbohydrate binding...
7.
Eck J, Langer M, Mockel B, Witthohn K, Zinke H, Lentzen H
Eur J Biochem
. 1999 Oct;
265(2):788-97.
PMID: 10504411
Mistletoe lectin I (pML) and its isoforms ML II and III constitute the active principle in extract preparations from mistletoe, commonly used as immunomodulator in adjuvant tumour therapy. The heterodimeric...
8.
Eck J, Langer M, Mockel B, Baur A, Rothe M, Zinke H, et al.
Eur J Biochem
. 1999 Sep;
264(3):775-84.
PMID: 10491123
Mistletoe lectin I (MLI) is the major active constituent of mistletoe extracts, which are widely used for adjuvant tumour therapy. The 66-kDa heterodimeric disulphide-linked glycoprotein is classified as type II...
9.
Mengs U, Witthohn K, Schwarz T, Lentzen H
Wien Med Wochenschr
. 1999 Sep;
149(8-10):262-4.
PMID: 10483695
It could be shown from several experiments that carbohydrate-binding mistletoe lectins represent the pharmacologically active constituents of mistletoe extracts. On the basis of these findings, it was possible to develop...
10.
Hajto T, Hostanska K, Weber K, Zinke H, Fischer J, Mengs U, et al.
Nat Immun
. 1998 Oct;
16(1):34-46.
PMID: 9789123
A plant lectin, Viscum album agglutinin-I (VAA-I) has been shown to increase the number and cytotoxic activity of natural killer (NK) cells in animal models, but the mechanisms underlying these...