H L Reeves
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Explore the profile of H L Reeves including associated specialties, affiliations and a list of published articles.
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10
Citations
508
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Recent Articles
1.
Liu Y, Patman G, Leathart J, Piguet A, Burt A, Dufour J, et al.
J Hepatol
. 2014 Mar;
61(1):75-81.
PMID: 24607626
Background & Aims: Subtle inter-patient genetic variation and environmental factors combine to determine disease progression in non-alcoholic fatty liver disease (NAFLD). Carriage of the PNPLA3 rs738409 c.444C >G minor allele...
2.
Lochan R, Daly A, Reeves H, Charnley R
J Oncol
. 2011 May;
2011:215985.
PMID: 21547248
Aim. To examine interaction between history of cancer in first-degree relatives and tobacco smoking in index patients of pancreatic adenocarcinoma. Methods. We carried out a case-control involving 113 patients with...
3.
Lochan R, Daly A, Reeves H, Charnley R
Br J Surg
. 2007 Dec;
95(1):22-32.
PMID: 18076020
Background: The strongest risk factors for pancreatic adenocarcinoma are tobacco smoking and increasing age. However, only a few smokers or elderly individuals develop the disease and genetic factors are also...
4.
Chattopadhyay D, Manas D, Reeves H
Curr Pharm Des
. 2007 Nov;
13(32):3292-300.
PMID: 18045181
Present treatment options for hepatocellular cancer (HCC) are limited to those individuals with good liver function and early stage disease. Unfortunately this includes only a minority of patients, few of...
5.
Narla G, Heath K, Reeves H, Li D, Giono L, Kimmelman A, et al.
Science
. 2001 Dec;
294(5551):2563-6.
PMID: 11752579
Kruppel-like factor 6 (KLF6) is a zinc finger transcription factor of unknown function. Here, we show that the KLF6 gene is mutated in a subset of human prostate cancer. Loss-of-heterozygosity...
6.
Reeves H, Dack C, Peak M, Burt A, Day C
J Hepatol
. 2000 Mar;
32(3):465-72.
PMID: 10735617
Background/aims: The signal cascades involved in the activation of hepatic stellate cells (HSC) are largely unknown. Factors initiating activation include tumour necrosis factor (TNF)-alpha, transforming growth factor (TGF)-beta, endothelin, and...
7.
Reeves H, Thompson M, Dack C, Burt A, Day C
Hepatology
. 1999 Dec;
31(1):95-100.
PMID: 10613733
Platelet-derived growth factor (PDGF) is the most potent mitogen for hepatic stellate cells (HSCs) in vitro. The aim of this study was to investigate the role of the lipid-derived second...
8.
Reeves H, Francis R, Manas D, Hudson M, Day C
Liver Transpl Surg
. 1998 Sep;
4(5):404-9.
PMID: 9724478
Osteoporosis is common in patients with chronic cholestatic liver disease, and atraumatic spinal fracture is a recognized complication after orthotopic liver transplantation. Bisphosphonates are potent inhibitors of osteoclast bone resorption...
9.
Reeves H, Burt A, Wood S, Day C
J Hepatol
. 1996 Nov;
25(5):677-83.
PMID: 8938545
Background/aims: There is now overwhelming evidence that hepatic stellate cells are the principal cells involved in hepatic fibrogenesis. In several different forms of liver injury it has been demonstrated that...
10.
Hulme L, Reeves H, Clothier R, Smith M, Balls M
Mol Toxicol
. 1987 Jan;
1(4):589-96.
PMID: 3509705
The FRAME in vitro cytotoxicity assay and a physicochemical parameter for metal ions (i.e., "softness," sigma p) were assessed for their ability to predict the in vivo acute toxicities of...