H L Klein
Overview
Explore the profile of H L Klein including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
1651
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Recent Articles
1.
Klein H
Genetics
. 2002 Jan;
159(4):1501-9.
PMID: 11779792
Genomic instability is one of the hallmarks of cancer cells and is often the causative factor in revealing recessive gene mutations that progress cells along the pathway to unregulated growth....
2.
Fan H, Merker R, Klein H
Mol Cell Biol
. 2001 Jul;
21(16):5459-70.
PMID: 11463828
We report on a novel role for a pre-mRNA splicing component in genome stability. The Hpr1 protein, a component of an RNA polymerase II complex and required for transcription elongation,...
3.
Klein H
Genetics
. 2001 Feb;
157(2):557-65.
PMID: 11156978
The SRS2 gene of Saccharomyces cerevisiae encodes a DNA helicase that is active in the postreplication repair pathway and homologous recombination. srs2 mutations are lethal in a rad54Delta background and...
4.
5.
SCHNEITER R, Guerra C, Lampl M, Tatzer V, Zellnig G, Klein H, et al.
Mol Cell Biol
. 2000 Apr;
20(9):2984-95.
PMID: 10757783
The yeast vacuole functions both as a degradative organelle and as a storage depot for small molecules and ions. Vacuoles are dynamic reticular structures that appear to alternately fuse and...
6.
SCHNEITER R, Guerra C, Lampl M, Gogg G, Kohlwein S, Klein H
Mol Cell Biol
. 1999 Apr;
19(5):3415-22.
PMID: 10207065
In a screen for mutants that display synthetic lethal interaction with hpr1Delta, a hyperrecombination mutant of Saccharomyces cerevisiae, we have isolated a novel cold-sensitive allele of the acetyl coenzyme A...
7.
Vainberg I, Lewis S, Rommelaere H, Ampe C, Vandekerckhove J, Klein H, et al.
Cell
. 1998 Jun;
93(5):863-73.
PMID: 9630229
We describe the discovery of a heterohexameric chaperone protein, prefoldin, based on its ability to capture unfolded actin. Prefoldin binds specifically to cytosolic chaperonin (c-cpn) and transfers target proteins to...
8.
Klein H
Genetics
. 1997 Dec;
147(4):1533-43.
PMID: 9409819
Most mitotic recombination and repair genes of Saccharomyces cerevisiae show no specificity of action for the genome ploidy. We describe here a novel repair and recombination gene that is specific...
9.
Fan H, Cheng K, Klein H
Genetics
. 1996 Mar;
142(3):749-59.
PMID: 8849885
The soh1, soh2 and soh4 mutants were isolated as suppressors of the temperature-dependent growth of the hyperrecombination mutant hpr1 of Saccharomyces cerevisiae. Cloning and sequence analysis of these suppressor genes...
10.
Zhang Y, Klein H, Schneider R
Gene
. 1995 Oct;
163(2):283-8.
PMID: 7590282
Eukaryotic translation initiation factor eIF-4E is essential for protein synthesis and cell viability. eIF-4E participates in formation of an m7GTP-cap binding protein complex that mediates association of 40S ribosomal subunits...