H Knauf
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Explore the profile of H Knauf including associated specialties, affiliations and a list of published articles.
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Articles
108
Citations
535
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Recent Articles
1.
Knauf H, Mutschler E, Velazquez H, Giebisch G
Eur J Clin Pharmacol
. 2009 Feb;
65(5):465-72.
PMID: 19229529
Background: Resistance to high-dose loop diuretics can be overcome either by co-administration with thiazides or by treatment with medium-dose loop diuretics combined with thiazides. Combination therapy has been proven to...
2.
Knauf H, Bailey M, Hasenfuss G, Mutschler E
Eur J Clin Pharmacol
. 2006 Sep;
62(11):885-92.
PMID: 16964522
Objective: Thiazide diuretics are known to induce a transient fall of the glomerular filtration rate (GFR), which, in turn, reduces tubular Na(+) load. This tubuloglomerular feedback (TGF) curtails the natriuretic...
3.
Emeriau J, Knauf H, Pujadas J, Calvo-Gomez C, Abate G, Leonetti G, et al.
J Hypertens
. 2001 Feb;
19(2):343-50.
PMID: 11212979
Objective: To analyse the efficacy of indapamide sustained-release (SR) 1.5 mg in reducing blood pressure versus amlodipine 5 mg and hydrochlorothiazide 25 mg, in elderly hypertensive patients. Design: Double-blind, randomized,...
4.
Mutschler E, Knauf H
Clin Pharmacokinet
. 1999 Sep;
37 Suppl 1:1-6.
PMID: 10491727
The principal advantages to be gained from controlling the variables of drug release in sustained release formulations are as follows: (i) a more uniform plasma drug profile with fewer occasions...
5.
Knauf H, Mutschler E
Clin Pharmacokinet
. 1998 Feb;
34(1):1-24.
PMID: 9474471
The new loop diuretic torasemide belongs to the pyridine sulfonylurea class. It is well absorbed and yields a bioavailablity of about 80% in healthy individuals, even higher in patients with...
6.
Mohrke W, Knauf H, Mutschler E
Int J Clin Pharmacol Ther
. 1997 Nov;
35(10):447-52.
PMID: 9352394
Although triamterene has been in clinical use for over 30 years, the linearity of triamterene kinetics was not systematically tested. Moreover, although triamterene is mostly applied concomitantly with thiazide-type diuretics...
7.
Knauf H, Mutschler E
J Cardiovasc Pharmacol
. 1997 Mar;
29(3):367-72.
PMID: 9125675
Diuretic therapy in edematous diseases often yields an inadequate natriuretic response ("diuretic resistance"). To study the functional changes in patients with congestive heart failure, liver cirrhosis with ascites, and nephrotic...
8.
Verwiebe R, Knauf H
Fortschr Med
. 1995 Oct;
113(29):418-22.
PMID: 7498873
In the conservative and dialysis treatment of renal disease in the elderly, the methods employed are the same as those applied in the young patient. The various procedures for the...
9.
Knauf H, Mutschler E
J Cardiovasc Pharmacol
. 1995 Sep;
26(3):394-400.
PMID: 8583780
In the absence of formal clinical trials, the efficacy of thiazide diuretics in patients with renal impairment remains in doubt. Our study was therefore designed to evaluate the separate and...
10.