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H Jan Guchelaar

Explore the profile of H Jan Guchelaar including associated specialties, affiliations and a list of published articles. Areas
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1.
van Staveren M, Guchelaar H, van Kuilenburg A, Gelderblom H, Maring J
Pharmacogenomics J . 2013 Jul; 13(5):389-95. PMID: 23856855
5-Fluorouracil (5-FU) is rapidly degraded by dihyropyrimidine dehydrogenase (DPD). Therefore, DPD deficiency can lead to severe toxicity or even death following treatment with 5-FU or capecitabine. Different tests based on...