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H Hammad

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Articles 32
Citations 913
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Recent Articles
11.
Rochlitzer S, Veres T, Kuhne K, Prenzler F, Pilzner C, Knothe S, et al.
Clin Exp Allergy . 2011 Jul; 41(11):1609-21. PMID: 21752117
Background: The neuropeptide calcitonin gene-related peptide (CGRP) is released in the lung by sensory nerves during allergic airway responses. Pulmonary dendritic cells (DC) orchestrating the allergic inflammation could be affected...
12.
Bousquet J, Anto J, Auffray C, Akdis M, Cambon-Thomsen A, Keil T, et al.
Allergy . 2011 Jan; 66(5):596-604. PMID: 21261657
The origin of the epidemic of IgE-associated (allergic) diseases is unclear. MeDALL (Mechanisms of the Development of ALLergy), an FP7 European Union project (No. 264357), aims to generate novel knowledge...
13.
Hammad H, Lambrecht B
Allergy . 2011 Jan; 66(5):579-87. PMID: 21251015
Because they can recognize and sample inhaled allergens, dendritic cells (DC) have been shown to be responsible for the initiation and maintenance of adaptive Th2 responses in asthma. It is...
14.
Krysko O, Holtappels G, Zhang N, Kubica M, Deswarte K, Derycke L, et al.
Allergy . 2010 Oct; 66(3):396-403. PMID: 20973804
Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by biased Th2 inflammation and CRS without nasal polyps (CRSsNP) by a Th1 immune response. Colonization by Staphylococcus aureus is increased...
15.
Ten Berge B, Muskens F, KleinJan A, Hammad H, Hoogsteden H, Lambrecht B, et al.
J Immunol Methods . 2009 Oct; 351(1-2):13-23. PMID: 19804781
Background: Dendritic cells (DCs) play a pivotal role in linking the innate and adaptive immune response and have been implicated in a variety of pulmonary diseases. Currently, studies on the...
16.
Perros F, Hoogsteden H, Coyle A, Lambrecht B, Hammad H
Allergy . 2009 Jul; 64(7):995-1002. PMID: 19630858
Background: As Th2 type lymphocytes orchestrate the cardinal features of allergic asthma, inhibiting their recruitment to the lungs could be of therapeutic benefit. Although human Th2 cells express the CCR4...
17.
Smits H, Gloudemans A, van Nimwegen M, Willart M, Soullie T, Muskens F, et al.
Mucosal Immunol . 2009 May; 2(4):331-9. PMID: 19404246
In healthy individuals, humoral immune responses to allergens consist of serum IgA and IgG4, whereas cellular immune responses are controlled by regulatory T (Treg) cells. In search of new compounds...
18.
Lambrecht B, Hammad H
Chem Immunol Allergy . 2008 Sep; 94:189-200. PMID: 18802348
Dendritic cells (DCs) are crucial in determining the functional outcome of allergen encounter in the lung. Antigen presentation by myeloid DCs leads to Th2 sensitization typical of allergic disease, whereas...
19.
Hegmans J, Hemmes A, Hammad H, Boon L, Hoogsteden H, Lambrecht B
Eur Respir J . 2006 Mar; 27(6):1086-95. PMID: 16540497
Malignant mesothelioma is a cancer with dismal prognosis. The objective of the present study was to address the role of the immune system, tumour micro-environment and potential immunosuppression in mesothelioma....
20.
Hammad H, de Vries V, Maldonado-Lopez R, Moser M, Maliszewski C, Hoogsteden H, et al.
Clin Exp Allergy . 2005 Jan; 34(12):1834-40. PMID: 15663556
Background: Different subsets of dendritic cells (DCs), identified in mouse spleen by their differential expression of CD8 alpha, can induce different T-helper (Th) responses after systemic administration. CD8 alpha(-) DCs...