H Bauke Albada
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Explore the profile of H Bauke Albada including associated specialties, affiliations and a list of published articles.
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24
Citations
384
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Recent Articles
1.
Albada H, Golub E, Willner I
Chem Sci
. 2018 Jul;
7(5):3092-3101.
PMID: 29997801
The rational design of a set of hemin/G-quadruplex (hGQ)-dopamine binding aptamer (DBA) conjugates, acting as nucleoapzymes, is described. The nucleoapzyme constructs consist of a hGQ DNAzyme as a catalytic unit...
2.
Wenzel M, Prochnow P, Mowbray C, Vuong C, Hoxtermann S, Stepanek J, et al.
Front Cell Dev Biol
. 2016 Sep;
4:86.
PMID: 27617260
RWRWRW-NH2 (MP196) is an amphipathic hexapeptide that targets the bacterial cytoplasmic membrane and inhibits cellular respiration and cell wall synthesis. In previous studies it showed promising activity against Gram-positive bacteria...
3.
Albada H, de Vries J, Liu Q, Golub E, Klement N, Herrmann A, et al.
Chem Commun (Camb)
. 2016 Mar;
52(32):5561-4.
PMID: 27020540
Lipidated DNAzymes or a lipidated Cu(II)-complex and lipidated aptamer sequences form supramolecular assemblies of micellar nucleoapzymes for the enhanced oxidation of dopamine to aminochrome. The catalytic functions of the micellar...
4.
Golub E, Albada H, Liao W, Biniuri Y, Willner I
J Am Chem Soc
. 2015 Dec;
138(1):164-72.
PMID: 26652164
A novel concept to improve the catalytic functions of nucleic acids (DNAzymes) is introduced. The method involves the conjugation of a DNA recognition sequence (aptamer) to the catalytic DNAzyme, yielding...
5.
Wenzel M, Schriek P, Prochnow P, Albada H, Metzler-Nolte N, Bandow J
Biochim Biophys Acta
. 2015 Nov;
1858(5):1004-11.
PMID: 26603779
Antimicrobial peptides are a potent class of antibiotics. In the Gram-positive model organism Bacillus subtilis the synthetic peptide RWRWRW-NH2 integrates into the bacterial membrane and delocalizes essential peripheral membrane proteins...
6.
Balogh D, Aleman Garcia M, Albada H, Willner I
Angew Chem Int Ed Engl
. 2015 May;
54(40):11652-6.
PMID: 25959900
DNAzyme-capped mesoporous SiO2 nanoparticles (MP SiO2 NPs) are applied as stimuli-responsive containers for programmed synthesis. Three types of MP SiO2 NPs are prepared by loading the NPs with Cy3-DBCO (DBCO=dibenzocyclooctyl),...
7.
Albada H, Golub E, Willner I
J Comput Aided Mol Des
. 2015 Apr;
29(7):643-54.
PMID: 25877490
The binding properties of sequence-specific nucleic acids (aptamers) to low-molecular-weight ligands, macromolecules and even cells attract substantial scientific interest. These ligand-DNA complexes found different applications for sensing, nanomedicine, and DNA...
8.
Sharon E, Enkin N, Albada H, Willner I
Chem Commun (Camb)
. 2014 Dec;
51(6):1100-3.
PMID: 25449885
Two-sized luminescent nucleic acid-functionalized Ag nanoclusters (NCs) are implemented for the analysis and multiplexed detection of adenosine monophosphate, AMP, and of cocaine using aptamer-ligand complexes.
9.
Enkin N, Wang F, Sharon E, Albada H, Willner I
ACS Nano
. 2014 Oct;
8(11):11666-73.
PMID: 25327411
Luminescent nucleic acid-stabilized Ag nanoclusters (Ag NCs) are applied for the optical detection of DNA and for the multiplexed analysis of genes. Two different sensing modules including Ag NCs as...
10.
Albada H, Prochnow P, Bobersky S, Langklotz S, Schriek P, Bandow J, et al.
ACS Med Chem Lett
. 2014 Jun;
3(12):980-4.
PMID: 24900420
The attachment of lipids to C- or N-terminally positioned lysine side-chain amino groups increases the activity of a short synthetic (Arg-Trp)3 antimicrobial peptide significantly, making these peptides even active against...