H Aburatani
Overview
Explore the profile of H Aburatani including associated specialties, affiliations and a list of published articles.
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Articles
91
Citations
4039
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Recent Articles
1.
Tanabe Y, Hayashi T, Okada M, Aburatani H, Tonegawa S, Abiko K, et al.
Georgian Med News
. 2024 Aug;
(350):42-48.
PMID: 39089269
Material And Methods: Out of 334 patients with suspected uterine mesenchymal tumors, patients diagnosed with smooth muscle tumors of the uterus were selected from the pathological file. To investigate the...
2.
Kawabata K, Hayashi Y, Inoue D, Meguro H, Sakurai H, Fukuyama T, et al.
Leukemia
. 2017 Jul;
32(2):419-428.
PMID: 28720764
Both proto-oncogenic and tumor-suppressive functions have been reported for enhancer of zeste homolog 2 (EZH2). To investigate the effects of its inactivation, a mutant EZH2 lacking its catalytic domain was...
3.
Nakatsuka T, Tateishi K, Kudo Y, Yamamoto K, Nakagawa H, Fujiwara H, et al.
Oncogene
. 2017 Jul;
36(45):6262-6271.
PMID: 28692045
Epigenetic gene regulation linked to oncogenic pathways is an important focus of cancer research. KDM3A, a histone H3 lysine 9 (H3K9) demethylase, is known to have a pro-tumorigenic function. Here,...
4.
Raja E, Komuro A, Tanabe R, Sakai S, Ino Y, Saito N, et al.
Oncogene
. 2017 May;
36(35):4963-4974.
PMID: 28459464
Bone morphogenetic protein (BMP) signaling exerts antitumor activities in glioblastoma; however, its precise mechanisms remain to be elucidated. Here, we demonstrated that the BMP type I receptor ALK-2 (encoded by...
5.
Obinata D, Takayama K, Fujiwara K, Suzuki T, Tsutsumi S, Fukuda N, et al.
Oncogene
. 2016 Jun;
35(49):6350-6358.
PMID: 27270436
Androgen receptor (AR) functions as a ligand-dependent transcription factor to regulate its downstream signaling for prostate cancer progression. AR complex formation by multiple transcription factors is important for enhancer activity...
6.
Muto H, Sakata-Yanagimoto M, Nagae G, Shiozawa Y, Miyake Y, Yoshida K, et al.
Blood Cancer J
. 2014 Dec;
4:e264.
PMID: 25501021
TET2 (Ten Eleven Translocation 2) is a dioxygenase that converts methylcytosine (mC) to hydroxymethylcytosine (hmC). TET2 loss-of-function mutations are highly frequent in subtypes of T-cell lymphoma that harbor follicular helper...
7.
Haferlach T, Nagata Y, Grossmann V, Okuno Y, Bacher U, Nagae G, et al.
Leukemia
. 2013 Nov;
28(2):241-7.
PMID: 24220272
High-throughput DNA sequencing significantly contributed to diagnosis and prognostication in patients with myelodysplastic syndromes (MDS). We determined the biological and prognostic significance of genetic aberrations in MDS. In total, 944...
8.
Tanaka M, Suzuki H, Shibahara J, Kunita A, Isagawa T, Yoshimi A, et al.
Oncogene
. 2013 Jun;
33(19):2454-63.
PMID: 23752186
Despite frequent KRAS mutation, the early molecular mechanisms of pancreatic ductal adenocarcinoma (PDAC) development have not been fully elucidated. By tracking a potential regulator of another feature of PDAC precursors,...
9.
Shojima N, Hara K, Fujita H, Horikoshi M, Takahashi N, Takamoto I, et al.
Diabetologia
. 2012 Sep;
55(12):3318-30.
PMID: 22983607
Aims/hypothesis: Insufficient insulin secretion and reduced pancreatic beta cell mass are hallmarks of type 2 diabetes. Here, we focused on a family of serine-threonine kinases known as homeodomain-interacting protein kinases...
10.
Koyama-Nasu R, Nasu-Nishimura Y, Todo T, Ino Y, Saito N, Aburatani H, et al.
Oncogene
. 2012 Sep;
32(33):3840-5.
PMID: 22964630
Cancer stem cells are believed to be responsible for tumor initiation and development. Much current research on human brain tumors is focused on the stem-like properties of glioblastoma stem cells...