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H A Coker

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Articles 13
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1.
Chukwuani C, Onyemelukwe G, Okonkwo P, Coker H, Ifudu N
Clin Drug Investig . 2008 Mar; 16(4):279-88. PMID: 18370549
Objective: The antibacterial efficacy of fleroxacin was compared with that of ciprofloxacin in 72 adult Nigerian patients with typhoid fever. Patients And Methods: On inclusion into the study, patients were...
2.
Chukwuani C, Coker H, Oduola A, Sowunmi A, Ifudu N
Biol Pharm Bull . 2000 Aug; 23(8):968-72. PMID: 10963305
The absolute bioavailability (BA) of ciprofloxacin and fleroxacin were evaluated in 19 adult Nigerian male volunteers. Subjects meeting the selection criteria were randomized to receive treatment either with fleroxacin (200...
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Okonkwo C, Coker H, Agomo P, Ogunbanwo J, Mafe A, Agomo C, et al.
Trans R Soc Trop Med Hyg . 1999 Sep; 93(3):306-11. PMID: 10492767
Chlorpheniramine (CP), a histamine H1-receptor antagonist, enhances the efficacy of chloroquine (CQ) in acute uncomplicated falciparum malaria. The effects of this combination therapy on the pharmacokinetic disposition of CQ is,...
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Chukwuani C, Coker H, Oduola A, Ifudu N, Sowunmi A
Chemotherapy . 1998 Oct; 44(6):369-76. PMID: 9755295
The kinetics of absorption, distribution and elimination of ciprofloxacin and fleroxacin (following an intravenous dose of 200 mg), were evaluated in 24 adult healthy male Nigerian volunteers. Appropriate mathematical models...
6.
Adegunloye B, Omoniyi J, Owolabi O, Ajagbonna O, Sofola O, Coker H
Afr J Med Med Sci . 1996 Sep; 25(3):235-8. PMID: 10457797
The antihypertensive effect of aqueous extracts of the calyx of Hibiscus sabdariffa (HS) has been investigated in anaesthetized rats. Hibiscus sabdariffa caused a dose-dependent decrease in mean arterial pressure (MAP)...
7.
Adegunloye B, Sofola O, Coker H
Eur J Clin Pharmacol . 1993 Jan; 45(1):85-8. PMID: 8405035
We have studied the effects of mefloquine on isolated rat aorta. Mefloquine (10(-8) to 1.6 x 10(-4) mol.l-1) relaxed aortic rings precontracted with both noradrenaline (10(-7) mol.l-1) and potassium chloride...
8.
Coker H, THOMAS A, Akintonwa A
Bull Environ Contam Toxicol . 1991 Nov; 47(5):706-10. PMID: 1813084
No abstract available.
9.
Coker H, Essien E, Edoho E
Afr J Med Med Sci . 1990 Jun; 19(2):111-4. PMID: 2115725
Treatment of tinidazole with a mixture of hydrogen peroxide and acetic acid, or liver homogenate preparations, yields the N-3 oxide. This was identified by thin-layer chromatographic analysis on silica gel...
10.
Adebayo G, Coker H, Fagbure F
Fundam Clin Pharmacol . 1988 Jan; 2(6):541-9. PMID: 3240918
Renal effects of nifedipine were assessed in 3 groups of healthy normotensive volunteers. In the first group (N = 10), a single 20-mg dose of the slow-release formulation caused an...