Gwenola Boulday
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Explore the profile of Gwenola Boulday including associated specialties, affiliations and a list of published articles.
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26
Citations
1132
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Recent Articles
1.
Grdseloff N, Boulday G, Rodel C, Otten C, Vannier D, Cardoso C, et al.
Sci Rep
. 2023 Apr;
13(1):5572.
PMID: 37019926
The capillary-venous pathology cerebral cavernous malformation (CCM) is caused by loss of CCM1/Krev interaction trapped protein 1 (KRIT1), CCM2/MGC4607, or CCM3/PDCD10 in some endothelial cells. Mutations of CCM genes within...
2.
Cardoso C, Arnould M, De Luca C, Otten C, Abdelilah-Seyfried S, Heredia A, et al.
Stroke
. 2020 Jan;
51(4):1272-1278.
PMID: 31992178
Background and Purpose- Cerebral cavernous malformations (CCMs) are vascular malformations of the brain that lead to cerebral hemorrhages. A pharmacological treatment is needed especially for patients with nonoperable deep-seated lesions....
3.
Otten C, Knox J, Boulday G, Eymery M, Haniszewski M, Neuenschwander M, et al.
EMBO Mol Med
. 2018 Sep;
10(10).
PMID: 30181117
Cerebral cavernous malformations (CCMs) are vascular lesions in the central nervous system causing strokes and seizures which currently can only be treated through neurosurgery. The disease arises through changes in...
4.
Lisowska J, Rodel C, Manet S, Miroshnikova Y, Boyault C, Planus E, et al.
J Cell Sci
. 2018 Jul;
131(15).
PMID: 30030370
Endothelial integrity relies on a mechanical crosstalk between intercellular and cell-matrix interactions. This crosstalk is compromised in hemorrhagic vascular lesions of patients carrying loss-of-function mutations in cerebral cavernous malformation (CCM)...
5.
Gwinner F, Boulday G, Vandiedonck C, Arnould M, Cardoso C, Nikolayeva I, et al.
Bioinformatics
. 2016 Nov;
33(5):701-709.
PMID: 27797778
Motivation: Most computational approaches for the analysis of omics data in the context of interaction networks have very long running times, provide single or partial, often heuristic, solutions and/or contain...
6.
Bravi L, Rudini N, Cuttano R, Giampietro C, Maddaluno L, Ferrarini L, et al.
Proc Natl Acad Sci U S A
. 2015 Jun;
112(27):8421-6.
PMID: 26109568
Cerebral cavernous malformation (CCM) is a disease of the central nervous system causing hemorrhage-prone multiple lumen vascular malformations and very severe neurological consequences. At present, the only recommended treatment of...
7.
Schulz G, Wieland E, Wustehube-Lausch J, Boulday G, Moll I, Tournier-Lasserve E, et al.
Stroke
. 2015 Mar;
46(5):1337-43.
PMID: 25791711
Background And Purpose: Cerebral cavernous malformation (CCM) is a neurovascular dysplasia characterized by conglomerates of enlarged endothelial channels in the central nervous system, which are almost devoid of pericytes or...
8.
Renz M, Otten C, Faurobert E, Rudolph F, Zhu Y, Boulday G, et al.
Dev Cell
. 2015 Jan;
32(2):181-90.
PMID: 25625207
Mechanotransduction pathways are activated in response to biophysical stimuli during the development or homeostasis of organs and tissues. In zebrafish, the blood-flow-sensitive transcription factor Klf2a promotes VEGF-dependent angiogenesis. However, the...
9.
Herve D, Philippi A, Belbouab R, Zerah M, Chabrier S, Collardeau-Frachon S, et al.
Am J Hum Genet
. 2014 Mar;
94(3):385-94.
PMID: 24581742
Moyamoya is a cerebrovascular condition characterized by a progressive stenosis of the terminal part of the internal carotid arteries (ICAs) and the compensatory development of abnormal "moyamoya" vessels. The pathophysiological...
10.
Faurobert E, Rome C, Lisowska J, Manet-Dupe S, Boulday G, Malbouyres M, et al.
J Cell Biol
. 2013 Aug;
202(3):545-61.
PMID: 23918940
The endothelial CCM complex regulates blood vessel stability and permeability. Loss-of-function mutations in CCM genes are responsible for human cerebral cavernous malformations (CCMs), which are characterized by clusters of hemorrhagic...