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Guy Wheeler

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Articles 12
Citations 549
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Recent Articles
1.
Goncalves O, Wheeler G, Dalmay T, Dai H, Castro M, Castro P, et al.
RSC Adv . 2022 May; 9(22):12766-12783. PMID: 35515856
Early detection of cancer biomarkers can reduce cancer mortality rate. miRNAs are small non-coding RNAs whose expression changes upon the onset of various types of cancer. Biosensors that specifically detect...
2.
Ruiz-Tortola A, Prats-Quilez F, Gonzalez-Lucas D, Banuls M, Maquieira A, Wheeler G, et al.
Biomed Opt Express . 2018 Apr; 9(4):1717-1727. PMID: 29675313
A label-free sensor, based on the combination of silicon photonic bandgap (PBG) structures with immobilized molecular beacon (MB) probes, is experimentally developed. Complementary target oligonucleotides are specifically recognized through hybridization...
3.
Ruiz-Tortola A, Prats-Quilez F, Gonzalez-Lucas D, Banuls M, Maquieira A, Wheeler G, et al.
J Biophotonics . 2018 Apr; 11(10):e201800030. PMID: 29664230
An experimental study of the influence of the conformational change suffered by molecular beacon (MB) probes-upon the biorecognition of nucleic acid target oligonucleotides over evanescent wave photonic sensors-is reported. To...
4.
De Felice B, Annunziata A, Fiorentino G, Borra M, Biffali E, Coppola C, et al.
Neurogenetics . 2014 Aug; 15(4):243-53. PMID: 25130371
Amyotrophic lateral sclerosis (ALS) is a progressive and seriously disabling adult-onset neurological disease. Ninety percent of ALS patients are sporadic cases (sALS) with no clear genetic linkage. Accumulating evidence indicates...
5.
Swingler T, Wheeler G, Carmont V, Elliott H, Barter M, Abu-Elmagd M, et al.
Arthritis Rheum . 2011 Dec; 64(6):1909-19. PMID: 22143896
Objective: To use an in vitro model of chondrogenesis to identify microRNAs (miRNAs) with a functional role in cartilage homeostasis. Methods: The expression of miRNAs was measured in the ATDC5...
6.
Wheeler G, Tyler K
Biochim Biophys Acta . 2010 Dec; 1808(3):634-41. PMID: 21126508
Within the lateral organisation of plasma membranes of polarized cell types there exist heterogeneous microdomains of distinct lipid composition, the small size of which (10-200 nm) makes them difficult to...
7.
Redshaw N, Wheeler G, Hajihosseini M, Dalmay T
Brain Res . 2008 Dec; 1250:20-6. PMID: 19056356
microRNAs are short RNA molecules that are often expressed in specific tissues and regulate a variety of developmental processes. We used locked nucleic acid probes in in situ hybridisation reactions...
8.
Wheeler G, Valoczi A, Havelda Z, Dalmay T
DNA Cell Biol . 2007 May; 26(4):251-5. PMID: 17465891
MicroRNAs (miRNAs) are recently discovered short regulatory RNA molecules representing a new layer in posttranscriptional gene expression regulation. Although more than 450 human miRNAs have been identified, only a very...
9.
Tuddenham L, Wheeler G, Ntounia-Fousara S, Waters J, Hajihosseini M, Clark I, et al.
FEBS Lett . 2006 Jul; 580(17):4214-7. PMID: 16828749
MicroRNAs (miRNA) are short RNA molecules regulating the expression of specific mRNAs. We investigated the expression pattern and potential targets of mouse miR-140 and found that miR-140 is specifically expressed...
10.
Sweetman D, Rathjen T, Jefferson M, Wheeler G, Smith T, Wheeler G, et al.
Dev Dyn . 2006 Jun; 235(8):2185-91. PMID: 16804893
The microRNAs (miRNAs) are recently discovered short, noncoding RNAs, that regulate gene expression in metazoans. We have cloned short RNAs from chicken embryos and identified five new chicken miRNA genes....