Guy S Bewick
Overview
Explore the profile of Guy S Bewick including associated specialties, affiliations and a list of published articles.
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29
Citations
436
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Recent Articles
1.
Thompson K, Watson S, Zanato C, DallAngelo S, de Nooij J, Pace-Bonello B, et al.
Exp Physiol
. 2023 Sep;
109(1):81-99.
PMID: 37656490
A metabotropic glutamate receptor coupled to phospholipase D (PLD-mGluR) was discovered in the hippocampus over three decades ago. Its pharmacology and direct linkage to PLD activation are well established and...
2.
Lionikas A, Hernandez Cordero A, Kilikevicius A, Carroll A, Bewick G, Bunger L, et al.
Physiol Rep
. 2023 Aug;
11(15):e15793.
PMID: 37568262
Aims: Stanniocalcin-2 (STC2) has recently been implicated in human muscle mass variability by genetic analysis. Biochemically, STC2 inhibits the proteolytic activity of the metalloproteinase PAPP-A, which promotes muscle growth by...
3.
McIntosh J, Mekrouda I, Dashti M, Giuraniuc C, Banks R, Miles G, et al.
Front Mol Neurosci
. 2023 Jun;
16:1169075.
PMID: 37273905
Introduction: The ultimate deficit in amyotrophic lateral sclerosis (ALS) is neuromuscular junction (NMJ) loss, producing permanent paralysis, ultimately in respiratory muscles. However, understanding the functional and structural deficits at NMJs...
4.
Housley S, Powers R, Nardelli P, Lee S, Blum K, Bewick G, et al.
Exp Physiol
. 2023 Mar;
109(1):55-65.
PMID: 36966478
Muscle spindles encode mechanosensory information by mechanisms that remain only partially understood. Their complexity is expressed in mounting evidence of various molecular mechanisms that play essential roles in muscle mechanics,...
5.
Tucci P, Brown I, Bewick G, Pertwee R, Marini P
Int J Mol Sci
. 2023 Feb;
24(4).
PMID: 36835033
3-3'-Diindolylmethane (DIM) is a biologically active dimer derived from the endogenous conversion of indole-3-carbinol (I3C), a naturally occurring glucosinolate found in many cruciferous vegetables (i.e., ). DIM was the first...
6.
Marini P, Cowie P, Ayar A, Bewick G, Barrow J, Pertwee R, et al.
Int J Mol Sci
. 2023 Jan;
24(2).
PMID: 36674826
In this study, we have investigated a possible mechanism that enables CB/M receptor cross-talk, using SH-SY5Y cells as a model system. Our results show that M receptor activation initiates signaling...
7.
8.
Blecher R, Heinemann-Yerushalmi L, Assaraf E, Konstantin N, Chapman J, Cope T, et al.
Philos Trans R Soc Lond B Biol Sci
. 2018 Sep;
373(1759).
PMID: 30249776
Muscle spindles and Golgi tendon organs (GTOs) are two types of sensory receptors that respond to changes in length or tension of skeletal muscles. These mechanosensors have long been known...
9.
Rudling J, Drever B, Reid B, Bewick G
Int J Mol Sci
. 2018 Jul;
19(7).
PMID: 30004407
Neurotransmitter release during trains of activity usually involves two vesicle pools (readily releasable pool, or RRP, and reserve pool, or RP) and two exocytosis mechanisms ("full-collapse" and "kiss-and-run"). However, synaptic...
10.
Bewick G, Cahusac P, Banks R
J Vis Exp
. 2016 May;
(111).
PMID: 27213522
A novel dissection and recording technique is described for monitoring afferent firing evoked by mechanical displacement of hairs in the mouse pinna. The technique is very cost-effective and easily undertaken...