Guruprasad P Aithal
Overview
Explore the profile of Guruprasad P Aithal including associated specialties, affiliations and a list of published articles.
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228
Citations
7101
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Recent Articles
21.
Nakafero G, Card T, Grainge M, Williams H, Taal M, Aithal G, et al.
EClinicalMedicine
. 2023 Sep;
64:102213.
PMID: 37745026
Background: Patients established on thiopurines (e.g., azathioprine) are recommended to undergo three-monthly blood tests for the early detection of blood, liver, or kidney toxicity. These side-effects are uncommon during long-term...
22.
Atallah E, Welsh S, OCarrigan B, Oshaughnessy A, Dolapo I, Kerr A, et al.
JHEP Rep
. 2023 Sep;
5(10):100851.
PMID: 37727807
Background & Aims: Checkpoint inhibitors (CPI) account for increasing numbers of drug-induced liver injury (DILI) cases. We aimed to determine the incidence rate and risk factors associated with checkpoint inhibitor-induced...
23.
Grove J, Stephens C, Lucena M, Andrade R, Weber S, Gerbes A, et al.
Diagn Progn Res
. 2023 Sep;
7(1):18.
PMID: 37697410
A lack of biomarkers that detect drug-induced liver injury (DILI) accurately continues to hinder early- and late-stage drug development and remains a challenge in clinical practice. The Innovative Medicines Initiative's...
24.
Subhani M, Talat U, Knight H, Morling J, Jones K, Aithal G, et al.
Qual Health Res
. 2023 Sep;
33(13):1203-1217.
PMID: 37683106
Recovery narratives are personal stories of health problems and recovery. A systematic review proposed a conceptual framework characterising alcohol misuse recovery narratives, consisting of eight principal dimensions, each with types...
25.
Lonsmann I, Grove J, Haider A, Kaye P, Karsdal M, Leeming D, et al.
Biology (Basel)
. 2023 Aug;
12(8).
PMID: 37626973
Background: Identification of progressive liver disease necessitates the finding of novel non-invasive methods to identify and monitor patients in need of early intervention. Investigating patients with early-liver injury may help...
26.
Response to: Letter to the Editor by Trinh et al. Drug-induced liver injury registries are important
Bjornsson E, Lucena M, Andrade R, Aithal G
Liver Int
. 2023 Aug;
43(10):2325-2326.
PMID: 37592875
No abstract available.
27.
Thomson P, Fragkas N, Kafu L, Aithal G, Lucena M, Terracciano L, et al.
Allergy
. 2023 Jul;
79(1):200-214.
PMID: 37515456
Background: Exposure to nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (IBU) and naproxen (NAP) is associated with idiosyncratic drug-induced liver injury (DILI). Carboxylate bioactivation into reactive metabolites (e.g., acyl glucuronides,...
28.
Malaikah S, Willis S, Henson J, Sargeant J, Yates T, Thackray A, et al.
Int J Obes (Lond)
. 2023 Jul;
47(10):1000-1007.
PMID: 37491534
Background/objectives: Inadequate movement, excess adiposity, and insulin resistance augment cardiometabolic risk. This study examined the associations of objectively measured moderate-to-vigorous intensity physical activity (MVPA), sedentary time and cardiorespiratory fitness (CRF),...
29.
Grove J, Lo P, Shrine N, Barwell J, Wain L, Tobin M, et al.
JHEP Rep
. 2023 Jul;
5(8):100764.
PMID: 37484212
Background & Aims: Non-alcoholic fatty liver disease (NAFLD) is a complex trait with an estimated prevalence of 25% globally. We aimed to identify the genetic variant underlying a four-generation family...
30.
Nakafero G, Grainge M, Williams H, Card T, Taal M, Aithal G, et al.
BMJ
. 2023 May;
381:e074678.
PMID: 37253479
Objective: To develop and validate a prognostic model to inform risk stratified decisions on frequency of monitoring blood tests during long term methotrexate treatment. Design: Retrospective cohort study. Setting: Electronic...