Gurpreet Kaur Singhera
Overview
Explore the profile of Gurpreet Kaur Singhera including associated specialties, affiliations and a list of published articles.
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13
Citations
88
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Recent Articles
1.
Bhattarai P, Lu W, Hardikar A, Gaikwad A, Dey S, Shahzad A, et al.
Clin Sci (Lond)
. 2024 Aug;
138(17):1055-1070.
PMID: 39136529
We previously reported pulmonary arterial remodelling and active endothelial-to-mesenchymal transition (EndMT) in smokers and patients with early chronic obstructive pulmonary disease (COPD). In the present study, we aimed to evaluate...
2.
Shahzad A, Lu W, Dey S, Bhattarai P, Gaikwad A, Jaffar J, et al.
J Clin Med
. 2024 Apr;
13(7).
PMID: 38610892
: Idiopathic pulmonary fibrosis (IPF) is an irreversible lung fibrotic disorder of unknown cause. It has been reported that bacterial and viral co-infections exacerbate disease pathogenesis. These pathogens use adhesion...
3.
Eapen M, Lu W, Dey S, Chia C, Hardikar A, Hassan M, et al.
ERJ Open Res
. 2024 Mar;
10(2).
PMID: 38500797
Background: COPD patients suffer from dysregulated and suppressed immune functionality, determined by their loss of degranulating capacity. Here we provide crucial information on the presence of degranulated mast cells (MCs)...
4.
Gaikwad A, Eapen M, Dey S, Bhattarai P, Shahzad A, Chia C, et al.
J Clin Med
. 2024 Feb;
13(4).
PMID: 38398472
We have previously reported that endothelial-to-mesenchymal transition (EndMT) is an active process in patients with idiopathic pulmonary fibrosis (IPF) contributing to arterial remodelling. Here, we aim to quantify drivers of...
5.
Bhattarai P, Lu W, Hardikar A, Dey S, Gaikwad A, Shahzad A, et al.
ERJ Open Res
. 2024 Feb;
10(1).
PMID: 38348240
Background: We have previously reported pulmonary arterial remodelling in smokers and patients with early COPD, which can be attributed to endothelial to mesenchymal transition (EndMT). In this study, we aimed...
6.
Lu W, Eapen M, Hardikar A, Chia C, Robertson I, Singhera G, et al.
ERJ Open Res
. 2023 Dec;
9(6).
PMID: 38152085
Background: Epithelial-mesenchymal transition (EMT) might be central to lung cancer development in smokers and COPD. We illustrate EMT changes in a broader demographic of patient groups who were diagnosed with...
7.
Gaikwad A, Lu W, Dey S, Bhattarai P, Haug G, Larby J, et al.
ERJ Open Res
. 2023 Apr;
9(2).
PMID: 37077555
Background: We have previously reported arterial remodelling in patients with idiopathic pulmonary fibrosis (IPF) and suggested that endothelial-to-mesenchymal transition (EndMT) might be central to these changes. This study aims to...
8.
Bhattarai P, Lu W, Gaikwad A, Dey S, Chia C, Larby J, et al.
ERJ Open Res
. 2022 Dec;
8(4).
PMID: 36478915
Introduction: Pulmonary vascular remodelling in chronic obstructive pulmonary disease (COPD) has detrimental consequences for lung physiology. The aim of our study was to provide a comprehensive size-based morphometric quantification of...
9.
Gaikwad A, Lu W, Dey S, Bhattarai P, Chia C, Larby J, et al.
ERJ Open Res
. 2022 Mar;
8(1).
PMID: 35350273
Background: Idiopathic pulmonary fibrosis (IPF) is a progressive, irreversible fibrotic interstitial lung disease. We performed size-based quantitation of pulmonary arterial remodelling in IPF and examined the role of endothelial-to-mesenchymal transition...
10.
Lu W, Eapen M, Singhera G, Markos J, Haug G, Chia C, et al.
J Clin Med
. 2022 Feb;
11(3).
PMID: 35160229
We previously reported higher ACE2 levels in smokers and patients with COPD. The current study investigates if patients with interstitial lung diseases (ILDs) such as IPF and LAM have elevated...