Guorong Lu
Overview
Explore the profile of Guorong Lu including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
190
Followers
0
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Recent Articles
1.
Groppe J, Lu G, Tandang-Silvas M, Pathi A, Konda S, Wu J, et al.
Biomolecules
. 2023 Jul;
13(7).
PMID: 37509165
Although structurally similar to type II counterparts, type I or activin receptor-like kinases (ALKs) are set apart by a metastable helix-loop-helix (HLH) element preceding the protein kinase domain that, according...
2.
Lu G, Tandang-Silvas M, Dawson A, Dawson T, Groppe J
Bone
. 2018 Apr;
112:71-89.
PMID: 29626545
Heterotopic ossification (HO), the pathological extraskeletal formation of bone, can arise from blast injuries, severe burns, orthopedic procedures and gain-of-function mutations in a component of the bone morphogenetic protein (BMP)...
3.
Holcomb J, Jiang Y, Guan X, Trescott L, Lu G, Hou Y, et al.
Biochem Biophys Res Commun
. 2014 Apr;
448(2):169-74.
PMID: 24768637
The formation of CXCR2-NHERF1-PLCβ2 macromolecular complex in neutrophils regulates CXCR2 signaling and plays a key role in neutrophil chemotaxis and transepithelial neutrophilic migration. However, NHERF1 by itself, with only two...
4.
Holcomb J, Jiang Y, Lu G, Trescott L, Brunzelle J, Sirinupong N, et al.
Biochem Biophys Res Commun
. 2014 Mar;
446(1):399-403.
PMID: 24613836
The formation of CFTR-NHERF2-LPA2 macromolecular complex in airway epithelia regulates CFTR channel function and plays an important role in compartmentalized cAMP signaling. We previously have shown that disruption of the...
5.
Jiang Y, Lu G, Trescott L, Hou Y, Guan X, Wang S, et al.
PLoS One
. 2013 Dec;
8(12):e81904.
PMID: 24339979
NHERF1 is a PDZ adaptor protein that scaffolds the assembly of diverse signaling complexes and has been implicated in many cancers. However, little is known about the mechanism responsible for...
6.
Lu G, Wu Y, Jiang Y, Wang S, Hou Y, Guan X, et al.
PLoS One
. 2013 Oct;
8(10):e76219.
PMID: 24098448
Neutrophil plays an essential role in host defense against infection, but uncontrolled neutrophilic infiltration can cause inflammation and severe epithelial damage. We recently showed that CXCR2 formed a signaling complex...
7.
Huttemann M, Helling S, Sanderson T, Sinkler C, Samavati L, Mahapatra G, et al.
Biochim Biophys Acta
. 2011 Jul;
1817(4):598-609.
PMID: 21771582
Cytochrome c (Cytc) and cytochrome c oxidase (COX) catalyze the terminal reaction of the mitochondrial electron transport chain (ETC), the reduction of oxygen to water. This irreversible step is highly...
8.
Wang Z, Huang Z, Lu G, Lin L, Ferrari M
Am J Physiol Heart Circ Physiol
. 2009 Mar;
296(5):H1321-8.
PMID: 19304947
Exposure to an adverse intrauterine environment increases the risk of cardiovascular disease later in adult life. However, the time course relationship between prenatal hypoxia and the onset of atherosclerosis in...