Guoqiang Chang
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Explore the profile of Guoqiang Chang including associated specialties, affiliations and a list of published articles.
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21
Citations
615
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Recent Articles
1.
Zhang W, Han Y, Huang H, Su Y, Ren H, Qi C, et al.
J Neuroinflammation
. 2024 Nov;
21(1):313.
PMID: 39616380
Background: Neuromyelitis optica spectrum disorder (NMOSD) is an autoantibody-triggered central nervous system (CNS) demyelinating disease that primarily affects the spinal cord, optic nerves and brainstem. Among the first responders to...
2.
Yi N, Guan X, Chen X, Xie L, Zhang N, Liao J, et al.
Polymers (Basel)
. 2024 Sep;
16(18).
PMID: 39339027
Perovskite is an advanced optoelectronic semiconductor material that has garnered significant attention in recent years. However, its drawback lies in its environmental instability, limiting its practical applications. To tackle this...
3.
Chang G, Xie G, Ma L, Li P, Li L, Richard H
Neuro Oncol
. 2022 Oct;
25(5):841-853.
PMID: 36239338
Background: ALKBH5 is aberrantly activated and exerts critical roles in facilitating the development of glioblastoma. However, the underlying activation mechanism by which ALKBH5 protein is increased in glioblastoma is not...
4.
Cao S, Xiong Q, Ding B, Wang X, Wei F, Sun Q, et al.
Oxid Med Cell Longev
. 2022 Aug;
2022:9306614.
PMID: 35915613
As a previously discovered target of DNA damage, Na/H exchanger 1 (NHE1) plays a role in regulation of intracellular pH (pH) through the extrusion of intracellular proton (H) in exchange...
5.
Chang G, Shi L, Ye Y, Shi H, Zeng L, Tiwary S, et al.
Cancer Cell
. 2020 Oct;
38(6):857-871.e7.
PMID: 33125861
Brain metastasis is a major cause of cancer mortality, but its molecular mechanisms are severely understudied. In addition, little is known regarding the role of mA reader YTHDF3 in human...
6.
Chen Y, Fang R, Yue C, Chang G, Li P, Guo Q, et al.
Cancer Res
. 2020 Jan;
80(5):1049-1063.
PMID: 31888886
Wnt/β-catenin signaling activates the transcription of target genes to regulate stem cells and cancer development. However, the contribution of epigenetic regulation to this process is unknown. Here, we report that...
7.
Yang C, Yang Y, Ma L, Zhang G, Shi F, Yan Y, et al.
Int J Mol Med
. 2019 Jan;
43(3):1395-1405.
PMID: 30628649
Neuromyelitis optica (NMO) is a refractory autoimmune inflammatory disease of the central nervous system without an effective cure. Autologous bone marrow‑derived mesenchymal stem cells (BM‑MSCs) are considered to be promising...
8.
Ma L, Lin K, Chang G, Chen Y, Yue C, Guo Q, et al.
Cancer Res
. 2018 Nov;
79(1):72-85.
PMID: 30425057
Aberrant activation of β-catenin signaling is a critical driver for tumorigenesis, but the mechanism underlying this activation is not completely understood. In this study, we demonstrate a critical role of...
9.
Chang G, Leu J, Ma L, Xie K, Huang S
Cytokine
. 2018 Jul;
118:35-41.
PMID: 30017390
Among myriads of distinct chemical modification in RNAs, the dynamic, reversible and fine-tuned methylation of N-methyladenosine (mA) is the most prevalent modification in eukaryotic mRNAs. This RNA mark is generated...
10.
Zhang C, Gong Y, Zhu W, Qi Y, Yang C, Fu Y, et al.
J Immunol
. 2016 Aug;
197(7):2610-7.
PMID: 27543617
Myasthenia gravis (MG) is a chronic humoral immunity-mediated autoimmune disorder of the neuromuscular junction characterized by muscle weakness. Follicular helper T (Tfh) cells may be the key Th cell subset...