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Guojun Lu

Explore the profile of Guojun Lu including associated specialties, affiliations and a list of published articles. Areas
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Articles 31
Citations 692
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Recent Articles
1.
Lu G, Liu H, Wang H, Luo S, Du M, Christiani D, et al.
Int J Cancer . 2024 Dec; PMID: 39707607
Fibroblasts are important components in the tumor microenvironment and can affect tumor progression and metastasis. However, the roles of genetic variants of the fibroblast-related genes (FRGs) in the prognosis of...
2.
Lu G, Liu H, Wang H, Tang X, Luo S, Du M, et al.
Front Immunol . 2024 Oct; 15:1455927. PMID: 39416786
Background: T cell exhaustion is a state in which T cells become dysfunctional and is associated with a decreased efficacy of immune checkpoint inhibitors. Lung cancer has the highest mortality...
3.
Ou J, Xing M, Lu G, Wan C, Li K, Jiang W, et al.
Nano Lett . 2024 Oct; 24(42):13118-13125. PMID: 39365010
Peptide vaccines induce specific neutralizing antibodies and are effective in disease prevention and treatment. However, peptide antigens have a low immunogenicity and are unstable, requiring efficient vaccine carriers to enhance...
4.
Wang H, Liu H, Tang X, Lu G, Luo S, Du M, et al.
Int J Cancer . 2024 Sep; 156(4):744-755. PMID: 39319523
Ferroptosis, a form of regulated cell death, is characterized by iron-dependent lipid peroxidation. It is recognized increasingly for its pivotal role in both cancer development and the response to cancer...
5.
Lu G, Liu H, Wang H, Tang X, Luo S, Du M, et al.
Front Immunol . 2024 Aug; 15:1440454. PMID: 39176091
B cells are adaptive immune cells in the tumor microenvironment and play an important role in tumor development and metastasis. However, the roles of genetic variants of the immunity B...
6.
Wang H, Liu H, Lu G, Tang X, Luo S, Du M, et al.
Cancer Med . 2024 Aug; 13(15):e70073. PMID: 39096122
Background: Hypoxia is often involved in tumor microenvironment, and the hypoxia-induced signaling pathways play a key role in aggressive cancer phenotypes, including angiogenesis, immune evasion, and therapy resistance. However, it...
7.
Wan C, Ju X, Xu D, Ou J, Zhu M, Lu G, et al.
Acta Biomater . 2024 Jul; 185:215-225. PMID: 39067645
Pseudomonas aeruginosa (P. aeruginosa) is a major pathogen that causes infectious diseases. It has high tendency to form biofilms, resulting in the failure of traditional antibiotic therapies. Inspired by the...
8.
Lu G, Ju X, Zhu M, Ou J, Xu D, Li K, et al.
Adv Healthc Mater . 2024 Feb; 13(17):e2303755. PMID: 38424475
Short-chain antifungal peptides (AFPs) inspired by histatin 5 have been designed to address the problem of antifungal drug resistance. These AFPs demonstrate remarkable antifungal activity, with a minimal inhibitory concentration...
9.
Xu D, Ju X, Zhu M, Ou J, Lu G, Wan C, et al.
J Colloid Interface Sci . 2023 Mar; 641:126-134. PMID: 36931211
Surface-associated microbe contamination by Gram-negative bacteria poses a serious problem in medical care. Cationic peptides or polymers are the main materials used for antibacterial surface coating, but the positive charge...
10.
Ou J, Zhu M, Ju X, Xu D, Lu G, Li K, et al.
Nano Lett . 2023 Jan; 23(5):2056-2064. PMID: 36695738
The phenotype of tumor-associated macrophages plays an important role in their function of regulating the tumor immune microenvironment. The M1-phenotype macrophages display tumor-killing and immune activating functions. Here we show...