Guo-Qiang Chang
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Explore the profile of Guo-Qiang Chang including associated specialties, affiliations and a list of published articles.
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12
Citations
80
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Recent Articles
1.
Zhang D, Wang R, Li T, Zhou J, Chang G, Zhao N, et al.
Sci Rep
. 2016 Feb;
6:21890.
PMID: 26902096
Soluble receptor for advanced glycation end products (sRAGE) is an anti-inflammatory factor that mitigates the proinflammatory effects of high mobility group box 1 (HMGB1). The aim of this study was...
2.
Li Y, Chang G, Liu Y, Gong Y, Yang C, Wood K, et al.
Neurosci Bull
. 2015 May;
31(6):755-62.
PMID: 25958190
Intracerebral hemorrhage (ICH) leads to high rates of death and disability. The pronounced inflammatory reactions that rapidly follow ICH contribute to disease progression. Our recent clinical trial demonstrated that oral...
3.
Li Y, Zhang F, Qi Y, Chang G, Fu Y, Su L, et al.
J Neuroimmunol
. 2014 Dec;
278:239-46.
PMID: 25468778
While follicular helper T (Tfh) cells have been shown to be involved in many autoimmune diseases, the association of Tfh cells with the disease activity of neuromyelitis optica spectrum disorders...
4.
Zhang Y, Li H, Chang G, Zhang H, Wang J, Lin Y, et al.
Zhongguo Shi Yan Xue Ye Xue Za Zhi
. 2013 Sep;
21(4):861-5.
PMID: 23998575
This study was aimed to investigate the influence of short hairpin RNA (shRNA) on proliferation of human leukemia cell line THP-1. The shRNA targeting the site 732-752 of DOT1L mRNA...
5.
Gao W, Zhang Y, Zhang H, Jin W, Chang G, Zhang H, et al.
Zhongguo Shi Yan Xue Ye Xue Za Zhi
. 2013 Mar;
21(1):45-8.
PMID: 23484689
This study was purposed to explore the changes of possible angiogenetic factors other than VEGF after inhibition of NHE1 and their related mechanisms. The K562 cells were treated by NHE1...
6.
Hu R, Jin W, Chang G, Lin Y, Wang J, Ru Y, et al.
Zhongguo Shi Yan Xue Ye Xue Za Zhi
. 2012 Dec;
20(6):1341-5.
PMID: 23257429
This study was aimed to investigate whether the inhibition of NHE1 activity and intracellular acidification can reverse resistance of leukemia cells to the imatinib and to explore downstream signal molecule...
7.
Wang L, Chang G, Zhang H, Wang J, Lin Y, Jin W, et al.
Genes Cells
. 2012 Jan;
17(3):205-17.
PMID: 22251225
Multidrug resistance (MDR) is a major problem facing patients with cancer. Although Neutrophil gelatinase-associated lipocalin (NGAL) is highly expressed in various cancers, the possible role of NGAL in MDR is...
8.
Li H, Wang L, Wang J, Chang G, Jin W, Lin Y, et al.
Zhongguo Shi Yan Xue Ye Xue Za Zhi
. 2011 Aug;
19(4):857-60.
PMID: 21867601
This study was aimed to investigate the expression of Na(+)/H(+) exchanger 1 (NHE1) in K562 and HL-60 cells undergoing DNA damage induced by etoposide and to elucidate the regulating mechanism....
9.
Wang R, Chang G, Li Q, Wang L, Jin W, Lin Y, et al.
Zhongguo Shi Yan Xue Ye Xue Za Zhi
. 2011 Jul;
19(3):666-70.
PMID: 21729546
The aim of this study was to investigate the effect of intracellular acidification on accumulation of rhodamine 123 (rh123) in non-mature cells with none or low expression of multidrug resistance...
10.
Jin W, Wang J, Chang G, Lin Y, Wang L, Li H, et al.
Zhongguo Shi Yan Xue Ye Xue Za Zhi
. 2011 Jul;
19(3):661-5.
PMID: 21729545
This study was purposed to investigate the effect of hypoxia microenvironment on K562 leukemic cell differentiation, and characteristics of NHE1 involvement in this process. The K562 cells were treated with...