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Guo-Chun Wang

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Citations 367
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Recent Articles
1.
Xiao X, Niu Y, Liu P, Zheng Y, Zhang M, Wang G, et al.
J Med Case Rep . 2024 Dec; 18(1):616. PMID: 39707462
Background: Polyarteritis nodosa is a relatively uncommon type of systemic necrotizing vasculitis that primarily affects medium-sized arteries. While gastrointestinal involvement is known in polyarteritis nodosa, heavy gastrointestinal bleeding due to...
2.
Xu Y, Cao Z, Lin S, Shu X, Lu X, Wang G, et al.
Clin Exp Rheumatol . 2023 Dec; 42(2):237-245. PMID: 38153165
Objectives: Anti-MDA5+ dermatomyositis was associated with poor prognosis due to the high incidence of rapid progressive interstitial lung disease, pulmonary infection. The aim of this study is to investigate the...
3.
Xu Y, Zhang Y, Yang H, Ye L, Chen F, Lu X, et al.
Rheumatology (Oxford) . 2022 Apr; 62(1):397-406. PMID: 35412602
Objective: To investigate the association between the anti-melanoma differentiation associated gene 5 (MDA5) IgG subclasses and prognosis of patients with dermatomyositis (DM)-associated interstitial lung disease (ILD). Methods: This retrospective study...
4.
Peng Q, Zhang Y, Liu Y, Liang L, Li W, Tian X, et al.
Arthritis Rheumatol . 2022 Jan; 74(6):1048-1058. PMID: 35077006
Objective: Myofiber necrosis is a significant pathologic characteristic of idiopathic inflammatory myopathies (IIMs), and its molecular mechanism is largely unknown. Necroptosis is a recently identified form of regulated necrotic cell...
5.
Liang L, Zhang Y, Shen Y, Song A, Li W, Ye L, et al.
Front Cell Dev Biol . 2021 Apr; 9:628128. PMID: 33842457
Background: Dermatomyositis (DM) associated rapidly progressive interstitial lung disease (RP-ILD) has high mortality rate and poor prognosis. Galectin-9 (Gal-9) plays multiple functions in immune regulation. We investigated Gal-9 expression in...
6.
Li Z, Hu J, Li X, Yang Y, Li X, Xu J, et al.
Adv Ther . 2020 Nov; 38(1):772-781. PMID: 33237533
Introduction: Baricitinib is an oral, selective inhibitor of Janus kinase which demonstrates clinical efficacy in patients with rheumatoid arthritis (RA). This report aims to analyze the onset time of baricitinib...
7.
Shen Y, Zhang Y, Huang Z, Wang G, Peng Q
Mediators Inflamm . 2020 Nov; 2020:7948095. PMID: 33192174
Objective: Soluble CD206 (sCD206) is considered a macrophage activation marker, and a previous study proved it as a potential biomarker to predict the severity of anti-melanoma differentiation-associated gene 5- (anti-MDA-5-)...
8.
Chen H, Yang H, Cheng Q, Ge Y, Peng Q, Zhang Y, et al.
Clin Transl Immunology . 2020 Oct; 9(10):e1195. PMID: 33082955
Objectives: To investigate the prevalence and clinical significance of anti-calreticulin autoantibodies (anti-CRT Ab) in a large cohort of idiopathic inflammatory myopathy (IIM) patients. Methods: Sera from 469 patients with IIM,...
9.
Yang Y, Li X, Zhang X, Bao C, Hu J, Xu J, et al.
Rheumatol Ther . 2020 Sep; 7(4):851-866. PMID: 32876903
Introduction: Baricitinib is an oral selective inhibitor of Janus kinase (JAK) 1 and JAK 2, which has demonstrated significant efficacy in patients with moderately to severely active rheumatoid arthritis (RA)....
10.
Liang L, Zhang Y, Chen H, Ye L, Li S, Lu X, et al.
Eur J Dermatol . 2020 Apr; PMID: 32293565
Background: Anti-Mi-2 antibody is a type of myositis-specific autoantibody found in idiopathic inflammatory myopathy patients. Objectives: To investigate the clinical features and long-term outcomes in anti-Mi-2-positive dermatomyositis (DM) patients. Materials...