Gunther Schlunck
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Explore the profile of Gunther Schlunck including associated specialties, affiliations and a list of published articles.
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103
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1460
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Recent Articles
1.
Tiwari S, Goldmann L, Lubke J, Prucker O, Martin G, Schlunck G, et al.
ACS Appl Mater Interfaces
. 2025 Jan;
17(6):8849-8861.
PMID: 39874588
Glaucoma, a leading cause of blindness, demands innovative and effective treatments that surpass the limitations of current drug and surgical interventions to lower intraocular pressure. This study describes the generation...
2.
Boneva S, Wolf J, Jung M, Prinz G, Chui T, Jauch J, et al.
J Neuroinflammation
. 2024 Nov;
21(1):297.
PMID: 39543723
Background: Despite great advances in proliferative diabetic retinopathy (PDR) therapy over the last decades, one third of treated patients continue to lose vision. While resident vitreous macrophages called hyalocytes have...
3.
Liang P, Ness J, Rapp J, Boneva S, Schwammle M, Jung M, et al.
J Neuroinflammation
. 2024 Sep;
21(1):230.
PMID: 39294742
Background: The IL-6 cytokine family, with its crucial and pleiotropic intracellular signaling pathway STAT3, is a promising target for treating vasoproliferative retinal diseases. Previous research has shown that IL-6 cis-signaling...
4.
Genotyping single point mutations in rd1 and rd8 mice using melting curve analysis of qPCR fragments
Schwammle M, Bucher F, Schlunck G, Martin G
Sci Rep
. 2024 Aug;
14(1):19909.
PMID: 39198547
PCR is tolerant to single nucleotide mismatches. Therefore, genotyping of point mutations by PCR requires special conditions for the amplification of allele-specific PCR fragments. MS-PCR (mutagenically separated PCR) is an...
5.
Schlunck G, Maier P, Maier B, Maier W, Strempel S, Reinhard T, et al.
Int J Mol Sci
. 2024 Jun;
25(11).
PMID: 38892316
The microbiome of the ocular surface has been characterised, but only limited information is available on a possible silent intraocular microbial colonisation in normal eyes. Therefore, we performed next-generation sequencing...
6.
Rapp J, Ness J, Liang P, Hug M, Agostini H, Schlunck G, et al.
J Vis Exp
. 2024 Jun;
(207).
PMID: 38884490
Angiogenesis plays a crucial role in both physiological and pathological processes within the body including tumor growth or neovascular eye disease. A detailed understanding of the underlying molecular mechanisms and...
7.
Kistenmacher S, Schwammle M, Martin G, Ulrich E, Tholen S, Schilling O, et al.
Cells
. 2024 Apr;
13(7.
PMID: 38607062
Limbal epithelial progenitor cells (LEPC) rely on their niche environment for proper functionality and self-renewal. While extracellular vesicles (EV), specifically small EVs (sEV), have been proposed to support LEPC homeostasis,...
8.
Wolfram L, Gimpel C, Schwammle M, Clark S, Bohringer D, Schlunck G
Sci Rep
. 2024 Mar;
14(1):7488.
PMID: 38553490
Alterations in the structure and composition of Bruch's membrane (BrM) and loss of retinal pigment epithelial (RPE) cells are associated with various ocular diseases, notably age-related macular degeneration (AMD) as...
9.
Lapp T, Kammrath Betancor P, Schlunck G, Auw-Hadrich C, Maier P, Lange C, et al.
Front Cell Infect Microbiol
. 2024 Jan;
13:1285676.
PMID: 38274739
Purpose: Corneal infections are a leading cause of visual impairment and blindness worldwide. Here we applied high-resolution transcriptomic profiling to assess the general and pathogen-specific molecular and cellular mechanisms during...
10.
Rapp J, Ness J, Wolf J, Hospach A, Liang P, Hug M, et al.
Biochim Biophys Acta Mol Basis Dis
. 2024 Jan;
1870(3):167028.
PMID: 38244944
In angiogenesis research, scientists need to carefully select appropriate in vitro models to test their hypotheses to minimize the risk for false negative or false positive study results. In this...