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Gunther Helms

Explore the profile of Gunther Helms including associated specialties, affiliations and a list of published articles. Areas
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Articles 69
Citations 1905
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Recent Articles
1.
Dreha-Kulaczewski S, Sahoo P, Preusse M, Gkalimani I, Dechent P, Helms G, et al.
J Inherit Metab Dis . 2024 Jan; 47(2):387-403. PMID: 38200656
Cerebral folate transport deficiency, caused by a genetic defect in folate receptor α, is a devastating neurometabolic disorder that, if untreated, leads to epileptic encephalopathy, psychomotor decline and hypomyelination. Currently,...
2.
Lipp I, Kirilina E, Edwards L, Pine K, Jager C, Grassle T, et al.
Magn Reson Med . 2022 Nov; 89(4):1385-1400. PMID: 36373175
Purpose: Magnetization transfer saturation ( ) is a useful marker to probe tissue macromolecular content and myelination in the brain. The increased -inhomogeneity at  T and significantly larger saturation pulse...
3.
Seidemo A, Wirestam R, Helms G, Markenroth Bloch K, Xu X, Bengzon J, et al.
NMR Biomed . 2022 Oct; 36(6):e4863. PMID: 36310022
Dynamic glucose-enhanced (DGE) MRI is used to study the signal intensity time course (tissue response curve) after D-glucose injection. D-glucose has potential as a biodegradable alternative or complement to gadolinium-based...
4.
Lundberg A, Lind E, Olsson H, Helms G, Knutsson L, Wirestam R
J Neuroimaging . 2022 Feb; 32(3):442-458. PMID: 35128747
Background And Purpose: Cerebral tissue oxygenation is a critical brain viability parameter, and the magnetic properties of hemoglobin offer the opportunity to noninvasively quantify oxygen extraction fraction (OEF) by magnetic...
5.
Olsson H, Andersen M, Kadhim M, Helms G
Magn Reson Med . 2022 Jan; 87(6):2637-2649. PMID: 35037283
Purpose: To map T and the local flip angle ( ) in human brain using a single MP3RAGE sequence with 3 rapid acquisitions of gradient echoes (RAGEs). Theory And Methods:...
6.
Emmenegger T, David G, Ashtarayeh M, Fritz F, Ellerbrock I, Helms G, et al.
Front Neurosci . 2021 Oct; 15:772745. PMID: 34690691
[This corrects the article DOI: 10.3389/fnins.2021.674719.].
7.
Seidemo A, Lehmann P, Rydhog A, Wirestam R, Helms G, Zhang Y, et al.
NMR Biomed . 2021 Sep; 35(2):e4624. PMID: 34585813
Dynamic glucose-enhanced (DGE) magnetic resonance imaging (MRI) has shown potential for tumor imaging using D-glucose as a biodegradable contrast agent. The DGE signal change is small at 3 T (around...
8.
Olsson H, Noven M, Latt J, Wirestam R, Helms G
Tomography . 2021 Sep; 7(3):434-451. PMID: 34564300
At field strengths of 7 T and above, -weighted imaging of human brain suffers increasingly from radiofrequency (RF) inhomogeneities. The well-known MP2RAGE (magnetization prepared two rapid acquisition gradient echoes) sequence...
9.
Emmenegger T, David G, Ashtarayeh M, Fritz F, Ellerbrock I, Helms G, et al.
Front Neurosci . 2021 Jul; 15:674719. PMID: 34290579
G-ratio weighted imaging is a non-invasive, MRI-based technique that aims at estimating an aggregated measure of relative myelination of axons across the entire brain white matter. The MR g-ratio and...
10.
Noven M, Olsson H, Helms G, Horne M, Nilsson M, Roll M
Hum Brain Mapp . 2021 Jul; 42(15):5037-5050. PMID: 34288240
People learn new languages with varying degrees of success but what are the neuroanatomical correlates of the difference in language-learning aptitude? In this study, we set out to investigate how...