Gunter P Wagner
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Explore the profile of Gunter P Wagner including associated specialties, affiliations and a list of published articles.
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183
Citations
7126
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Recent Articles
11.
Pavlicev M, Wagner G
iScience
. 2024 Apr;
27(5):109670.
PMID: 38665209
Biological function depends on the composition and structure of the organism, the latter describing the organization of interactions between parts. While cells in multicellular organisms are capable of a remarkable...
12.
Dighe A, Maziarz J, Ibrahim-Hashim A, Gatenby R, Kshitiz , Levchenko A, et al.
iScience
. 2024 Jan;
27(1):108593.
PMID: 38174318
Gene expression change is a dominant mode of evolution. Mutations, however, can affect gene expression in multiple cell types. Therefore, gene expression evolution in one cell type can lead to...
13.
14.
DiFrisco J, Love A, Wagner G
J Morphol
. 2022 Nov;
284(1):e21531.
PMID: 36317664
Given the pervasiveness of gene sharing in evolution and the extent of homology across the tree of life, why is everything not homologous with everything else? The continuity and overlapping...
15.
Pavlicev M, Wagner G
MedComm (2020)
. 2022 Oct;
3(4):e174.
PMID: 36186235
In this short paper, we argue that there is a fundamental connection between the medical sciences and evolutionary biology as both are sciences of biological variation. Medicine studies pathological variation...
16.
Ma X, Dighe A, Maziarz J, Neumann E, Erkenbrack E, Hei Y, et al.
Evol Med Public Health
. 2022 Sep;
10(1):447-462.
PMID: 36148042
CD44 is an extracellular matrix receptor implicated in cancer progression. CD44 increases the invasibility of skin (SF) and endometrial stromal fibroblasts (ESF) by cancer and trophoblast cells. We reasoned that...
17.
Ba Q, Hei Y, Dighe A, Li W, Maziarz J, Pak I, et al.
Sci Adv
. 2022 Sep;
8(36):eabn0756.
PMID: 36083897
Evolutionary profiling has been largely limited to the nucleotide level. Using consistent proteomic methods, we quantified proteomic and phosphoproteomic layers in fibroblasts from 11 common mammalian species, with transcriptomes as...
18.
Rytkonen K, Faux T, Mahmoudian M, Heinosalo T, Nnamani M, Perheentupa A, et al.
iScience
. 2022 May;
25(5):104235.
PMID: 35494227
Trimethylation of histone H3 at lysine 4 (H3K4me3) is a marker of active promoters. Broad H3K4me3 promoter domains have been associated with cell type identity, but H3K4me3 dynamics upon cellular...
19.
DiFrisco J, Wagner G, Love A
Semin Cell Dev Biol
. 2022 Apr;
145:3-12.
PMID: 35400563
A central topic in research at the intersection of development and evolution is the origin of novel traits. Despite progress on understanding how developmental mechanisms underlie patterns of diversity in...
20.
Love A, Wagner G
Evolution
. 2021 Dec;
76(3):394-413.
PMID: 34962651
It is widely accepted that stressful conditions can facilitate evolutionary change. The mechanisms elucidated thus far accomplish this with a generic increase in heritable variation that facilitates more rapid adaptive...