Gunnar P H Dietz
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Explore the profile of Gunnar P H Dietz including associated specialties, affiliations and a list of published articles.
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44
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802
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Recent Articles
11.
Liman J, Weishaupt J, Bahr M, Dietz G
Pharmaceuticals (Basel)
. 2016 Oct;
3(4):1232-1240.
PMID: 27713298
Cdk5 is essential for neuronal differentiation processes in the brain. Activation of Cdk5 requires the association with the mostly neuron-specific p35 or p39. Overactivation of CDK5 by cleavage of p35...
12.
Andersen K, Leander Johansen J, Hentzer M, Smith G, Dietz G
Front Cell Neurosci
. 2016 Jul;
10:164.
PMID: 27445691
The G-protein coupled receptor 139 (GPR139) is expressed specifically in the brain in areas of relevance for motor control. GPR139 function and signal transduction pathways are elusive, and results in...
13.
Isberg V, Andersen K, Bisig C, Dietz G, Brauner-Osborne H, Gloriam D
J Chem Inf Model
. 2014 May;
54(6):1553-7.
PMID: 24826842
GPR139 is an orphan G protein-coupled receptor expressed mainly in the central nervous system. We developed a pharmacophore model based on known GPR139 surrogate agonists which led us to propose...
14.
Doeppner T, Ewert T, Tonges L, Herz J, Zechariah A, ElAli A, et al.
Stem Cells
. 2012 May;
30(6):1297-310.
PMID: 22593021
Novel therapeutic concepts against cerebral ischemia focus on cell-based therapies in order to overcome some of the side effects of thrombolytic therapy. However, cell-based therapies are hampered because of restricted...
15.
Dietz G
Exp Neurol
. 2011 May;
231(1):1-10.
PMID: 21620833
Over the last decade, numerous studies have suggested that neuroglobin is able to protect against the effects of ischemia. However, such results have mostly been based on models using transgenic...
16.
Doeppner T, El Aanbouri M, Dietz G, Weise J, Schwarting S, Bahr M
Neurobiol Dis
. 2010 Jun;
40(1):265-76.
PMID: 20554038
Neural precursor cells (NPC) are an interesting tool in experimental stroke research, but their therapeutic potential is limited due to poor long-term survival. We therefore in vitro transduced subventricular zone-(SVZ)-derived...
17.
Dietz G
Curr Pharm Biotechnol
. 2010 Feb;
11(2):167-74.
PMID: 20166965
Cell-penetrating peptides (CPP), also called protein transduction domains (PTD), membrane-permeable peptides (MPP), or Trojan horse peptides, have been used in many different research areas. The delivery of heat shock proteins...
18.
Doeppner T, Dietz G, Weise J, Bahr M
Exp Neurol
. 2010 Feb;
223(2):548-56.
PMID: 20156439
Endogenous neurogenesis persists in the subgranular zone (SGZ) of the adult rodent brain. Cerebral ischemia stimulates endogenous neurogenesis involving proliferation, migration and differentiation of SGZ-derived neural precursor cells (NPC). However,...
19.
Bermel C, Tonges L, Planchamp V, Gillardon F, Weishaupt J, Dietz G, et al.
Mol Cell Neurosci
. 2009 Sep;
42(4):427-37.
PMID: 19782753
CNS regeneration is limited by lesion-induced neuronal apoptosis and an environment inhibiting axonal elongation. Inhibition of ROCK has been previously shown to promote regeneration in retinal ganglion cells (RGC) whereas...
20.
Frank T, Schlachetzki J, Goricke B, Meuer K, Rohde G, Dietz G, et al.
BMC Neurosci
. 2009 May;
10:49.
PMID: 19442279
Background: The hematopoietic Granulocyte-Colony Stimulating Factor (G-CSF) plays a crucial role in controlling the number of neutrophil progenitor cells. Its function is mediated via the G-CSF receptor, which was recently...