Gunasegaran Karupiah
Overview
Explore the profile of Gunasegaran Karupiah including associated specialties, affiliations and a list of published articles.
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37
Citations
1116
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Recent Articles
1.
Pandey P, Al Rumaih Z, Kels M, Ng E, Kc R, Malley R, et al.
Viruses
. 2023 Feb;
15(2).
PMID: 36851532
Influenza pneumonia is a severe complication caused by inflammation of the lungs following infection with seasonal and pandemic strains of influenza A virus (IAV), that can result in lung pathology,...
2.
Pandey P, Al Rumaih Z, Kels M, Ng E, Kc R, Chaudhri G, et al.
Proc Natl Acad Sci U S A
. 2022 Feb;
119(8).
PMID: 35177474
Viral causes of pneumonia pose constant threats to global public health, but there are no specific treatments currently available for the condition. Antivirals are ineffective when administered late after the...
3.
K C R, Leong K, Harkness N, Lachowicz J, Gautam S, Cooley L, et al.
Microb Genom
. 2021 Oct;
7(10).
PMID: 34605761
No abstract available.
4.
Pandey P, Karupiah G
FEBS J
. 2021 Feb;
289(4):883-900.
PMID: 33624419
Pneumonia is a serious complication associated with inflammation of the lungs due to infection with viral pathogens. Seasonal and pandemic influenza viruses, variola virus (agent of smallpox) and severe acute...
5.
Al Rumaih Z, Kels M, Ng E, Pandey P, Pontejo S, Alejo A, et al.
Proc Natl Acad Sci U S A
. 2020 Oct;
117(43):26885-26894.
PMID: 33046647
Ectromelia virus (ECTV) causes mousepox, a surrogate mouse model for smallpox caused by variola virus in humans. Both orthopoxviruses encode tumor necrosis factor receptor (TNFR) homologs or viral TNFR (vTNFR)....
6.
Kc R, Leong K, Harkness N, Lachowicz J, Gautam S, Cooley L, et al.
Microb Genom
. 2020 Jul;
6(8).
PMID: 32706329
Nontypeable (NTHi) colonizes human upper respiratory airways and plays a key role in the course and pathogenesis of acute exacerbations of chronic obstructive pulmonary disease (COPD). Currently, it is not...
7.
Kels M, Ng E, Al Rumaih Z, Pandey P, Ruuls S, Korner H, et al.
Proc Natl Acad Sci U S A
. 2020 Jun;
117(27):15935-15946.
PMID: 32571912
Excessive tumor necrosis factor (TNF) is known to cause significant pathology. Paradoxically, deficiency in TNF (TNF) also caused substantial pathology during respiratory ectromelia virus (ECTV) infection, a surrogate model for...
8.
Kc R, Leong K, McEwan B, Lachowicz J, Harkness N, Petrovski S, et al.
Microbiol Resour Announc
. 2020 May;
9(19).
PMID: 32381620
Nontypeable (NTHi) is an important cause of human illness, including pneumonia and acute exacerbations of chronic obstructive pulmonary disease (COPD). We report here the draft genome of an isolate of...
9.
Gowripalan A, Abbott C, McKenzie C, Chan W, Karupiah G, Levy L, et al.
Cell Microbiol
. 2020 Apr;
22(8):e13206.
PMID: 32237038
The induction of Smad signalling by the extracellular ligand TGF-β promotes tissue plasticity and cell migration in developmental and pathological contexts. Here, we show that vaccinia virus (VACV) stimulates the...
10.
Zammit N, Siggs O, Gray P, Horikawa K, Langley D, Walters S, et al.
Nat Immunol
. 2019 Sep;
20(10):1299-1310.
PMID: 31534238
Resisting and tolerating microbes are alternative strategies to survive infection, but little is known about the evolutionary mechanisms controlling this balance. Here genomic analyses of anatomically modern humans, extinct Denisovan...