Guillermo R Schinella
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Explore the profile of Guillermo R Schinella including associated specialties, affiliations and a list of published articles.
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27
Citations
391
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Recent Articles
1.
Maiztegui B, Villagarcia H, Roman C, Flores L, Prieto J, Castro M, et al.
Plants (Basel)
. 2023 Jul;
12(14).
PMID: 37514235
"Yerba mate" (YM), an aqueous extract of Ilex paraguariensis, has antioxidant, diuretic, cardio-protective and hypoglycaemic properties. Since its effect on the pancreatic islets remains unclear, we evaluated insulin sensitivity and...
2.
Prieto J, Schinella G
Antioxidants (Basel)
. 2022 Apr;
11(4).
PMID: 35453296
The relationship between lipid peroxidation and inflammation has been accepted as a paradigm in the field of topical inflammation. The underlying biochemical mechanisms may be summarised as unspecific oxidative damage...
3.
Rios J, Schinella G, Moragrega I
Molecules
. 2022 Mar;
27(6).
PMID: 35335130
Natural products can act as potential GABA modulators, avoiding the undesirable effects of traditional pharmacology used for the inhibition of the central nervous system such as benzodiazepines (BZD). Phenolics, especially...
4.
Gaddi G, Gisonno R, Rosu S, Curto L, Prieto E, Schinella G, et al.
Arch Biochem Biophys
. 2020 Mar;
685:108347.
PMID: 32194045
The reason that determines the pathological deposition of human apolipoprotein A-I variants inducing organ failure has been under research since the early description of natural mutations in patients. To shed...
5.
Gisonno R, Prieto E, Gorgojo J, Curto L, Rodriguez M, Rosu S, et al.
Biochim Biophys Acta Gen Subj
. 2020 Jan;
1864(4):129515.
PMID: 31904503
Background: Different protein conformations may be involved in the development of clinical manifestations associated with human amyloidosis. Although a fibrillar conformation is usually the signature of damage in the tissues...
6.
Arbelaez L, Ciocci Pardo A, Fantinelli J, Rojano B, Schinella G, Mosca S
Naunyn Schmiedebergs Arch Pharmacol
. 2019 Nov;
393(4):629-638.
PMID: 31776590
Purpose: To determine the actions of isoespintanol (Isoesp) on post-ischemic myocardial and mitochondrial alterations. Methods: Hearts removed from Wistar rats were perfused by 20 min. After this period, the coronary...
7.
Castro M, Villagarcia H, Nazar A, Arbelaez L, Massa M, Del Zotto H, et al.
J Ethnopharmacol
. 2019 Oct;
247:112263.
PMID: 31580944
Ethnopharmacological Relevance: Cocoa extracts rich in polyphenols are used as potential agent for treating diabetes. Cocoa polyphenols have been proved to ameliorate important hallmarks of type-2 diabetes (T2D). They can...
8.
Rios J, Andujar I, Schinella G, Francini F
Planta Med
. 2019 May;
85(11-12):825-839.
PMID: 31064029
Incretins are metabolic hormones released after a meal that increase insulin secretion from pancreatic -cells. The two main incretins are the intestinal peptides glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide. Both...
9.
Francini F, Schinella G, Rios J
Mini Rev Med Chem
. 2018 Nov;
19(11):880-901.
PMID: 30484403
Type-2 Diabetes (T2D) is a metabolic disease characterized by permanent hyperglycemia, whose development can be prevented or delayed by using therapeutic agents and implementing lifestyle changes. Some therapeutic alternatives include...
10.
Gavilanez Bunay T, Colareda G, Ragone M, Bonilla M, Rojano B, Schinella G, et al.
Phytomedicine
. 2018 Nov;
51:20-28.
PMID: 30466618
Background: Isoespintanol is a monoterpene isolated from the leaves of Oxandra xylopioides Diels. (Annonaceae) with antioxidant and antiinflammatory effects. It was of interest to know whether it has antispasmodic effects...