Guillem Ramis
Overview
Explore the profile of Guillem Ramis including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
8
Citations
51
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Almaran B, Ramis G, Fernandez de Mattos S, Villalonga P
Cells
. 2022 Dec;
11(23).
PMID: 36496976
Enhanced invasiveness is one of the defining biological traits of glioblastoma cells, which exhibit an infiltrative nature that severely hinders surgical resection. Among the molecular lesions responsible for GBM aggressiveness,...
2.
Sese B, Iniguez-Munoz S, Ensenyat-Mendez M, Llinas-Arias P, Ramis G, Orozco J, et al.
Cancers (Basel)
. 2022 May;
14(9).
PMID: 35565200
Background: Glioma stem cells (GSCs) have self-renewal and tumor-initiating capacities involved in drug resistance and immune evasion mechanisms in glioblastoma (GBM). Methods: Core-GSCs (c-GSCs) were identified by selecting cells co-expressing...
3.
Ximenis M, Sampedro A, Martinez-Crespo L, Ramis G, Orvay F, Costa A, et al.
Chem Commun (Camb)
. 2021 Feb;
57(22):2736-2739.
PMID: 33629090
Herein we report the design, synthesis and assessment of the first example of a squaramide-based self-immolative system triggered by an enzymatic reduction. We have proved that the release of the...
4.
Ramis G, Villalonga-Planells R, Serra-Sitjar M, Brell M, Fernandez de Mattos S, Villalonga P
Cell Oncol (Dordr)
. 2019 Apr;
42(4):521-536.
PMID: 30980364
Purpose: Although EGFR activation is a hallmark of glioblastoma (GBM), anti-EGFR therapy has so far not yielded the desired effects. Targeting PI3K/Akt has been proposed as a strategy to increase...
5.
Aceves-Luquero C, Galiana-Rosello C, Ramis G, Villalonga-Planells R, Garcia-Espana E, Fernandez de Mattos S, et al.
Biochem Pharmacol
. 2016 Jun;
115:28-42.
PMID: 27349984
A series of compounds containing the sulfonamide scaffold were synthesized and screened for their in vitro anticancer activity against a representative panel of human cancer cell lines, leading to the...
6.
Sampedro A, Villalonga-Planells R, Vega M, Ramis G, Fernandez de Mattos S, Villalonga P, et al.
Bioconjug Chem
. 2014 Jul;
25(8):1537-46.
PMID: 25036647
Cell internalization is a major issue in drug design. Although squaramide-based compounds are receiving much attention because of their interesting bioactivity, cell uptake and trafficking within cells of this type...
7.
Villalonga P, Fernandez de Mattos S, Ramis G, Obrador-Hevia A, Sampedro A, Rotger C, et al.
ChemMedChem
. 2012 Jul;
7(8):1472-80.
PMID: 22777958
We report the synthesis and biological evaluation of a new series of oligosquaramide-based macrocycles as anticancer agents. Compound 7, considered as representative of this series, exhibited significant antiproliferative activity against...
8.
Ramis G, Thomas-Moya E, Fernandez de Mattos S, Rodriguez J, Villalonga P
PLoS One
. 2012 Jun;
7(6):e38770.
PMID: 22701710
Enforced EGFR activation upon gene amplification and/or mutation is a common hallmark of malignant glioma. Small molecule EGFR tyrosine kinase inhibitors, such as erlotinib (Tarceva), have shown some activity in...