Guilherme V Rocha
Overview
Explore the profile of Guilherme V Rocha including associated specialties, affiliations and a list of published articles.
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6
Citations
68
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Recent Articles
1.
Walsh R, Lannan M, Wen Y, Wang X, Moreland C, Willency J, et al.
MAbs
. 2020 May;
12(1):1764829.
PMID: 32370596
Biologics have the potential to induce an immune response when used therapeutically. A number of assays are currently used preclinically to predict the risk of immunogenicity, but the validation of...
2.
Huang G, Rocha G, Pencina K, Cox K, Krishnan V, Henriksen K, et al.
J Clin Endocrinol Metab
. 2019 May;
104(9):3768-3778.
PMID: 31120518
Background: Biomarkers that predict response to anabolic therapies could expedite the development of function-promoting anabolic drugs. This study aimed to identify serum biomarkers that are responsive to testosterone administration and...
3.
Alakhras N, Qiu J, Rocha G, Witcher D, Koester A, You J, et al.
MAbs
. 2018 Jun;
10(6):913-921.
PMID: 29953319
Immunomodulatory monoclonal IgG1 antibodies developed for cancer and autoimmune disease have an inherent risk of systemic release of pro-inflammatory cytokines. In vitro cytokine release assays are currently used to predict...
4.
Roberts J, San Martin R, Piyarathna D, MacKrell J, Rocha G, Dodge J, et al.
Oncotarget
. 2017 Jun;
8(27):44447-44464.
PMID: 28591703
Whether vitamin D is chemopreventive and/or has potential therapeutically in prostate cancer is unresolved. One confounding factor is that many prostate cancers express a TMPRSS2:ERG fusion gene whose expression is...
5.
Hoffman R, Merrill J, Alarcon-Riquelme M, Petri M, Dow E, Nantz E, et al.
Arthritis Rheumatol
. 2016 Oct;
69(3):643-654.
PMID: 27723281
Objective: To characterize baseline gene expression and pharmacodynamically induced changes in whole blood gene expression in 1,760 systemic lupus erythematosus (SLE) patients from 2 phase III, 52-week, randomized, placebo-controlled, double-blind...
6.
Gifondorwa D, Thompson T, Wiley J, Culver A, Shetler P, Rocha G, et al.
Muscle Nerve
. 2016 Apr;
54(6):1120-1132.
PMID: 27074419
Introduction: There is evidence that supports a role for Vitamin D (Vit. D) in muscle. The exact mechanism by which Vit. D deficiency impairs muscle strength and function is not...