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Guanzhen Yu

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Articles 75
Citations 1553
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Recent Articles
1.
Xu X, Yun B, Zhao Y, Jin L, Zong Y, Yu G, et al.
Bioengineering (Basel) . 2025 Jan; 12(1). PMID: 39851283
Objective: We aim to construct an artificial intelligence (AI)-assisted nasal endoscopy diagnostic system capable of preliminary differentiation and identification of nasal neoplasia properties, as well as intraoperative tracking, providing an...
2.
Li C, Deng Y, Pan Y, Liao X, Xie H, Xue X, et al.
Heliyon . 2024 Sep; 10(18):e37347. PMID: 39309781
Purpose: The consistent use of metformin has been linked to a reduced incidence of neoplastic diseases among diabetic populations. As a preventive intervention, metformin may offer a more favorable risk-benefit...
3.
Liu F, Zhang Q, Zhang W, Cheng D, Zhang F, Deng Y, et al.
Anat Histol Embryol . 2024 Jul; 53(5):e13095. PMID: 39081054
An artificial intelligence (AI) model was designed to assist pathologists in diagnosing and quantifying structural changes in tongue lesions induced by chemical carcinogens. Using a tongue cancer model induced by...
4.
Jin X, Liu L, Liu D, Wu J, Wang C, Wang S, et al.
Cell Death Differ . 2024 Apr; 31(5):558-573. PMID: 38570607
Esophageal squamous cell carcinoma (ESCC) is a deadly malignancy with notable metabolic reprogramming, yet the pivotal metabolic feature driving ESCC progression remains elusive. Here, we show that methionine cycle exhibits...
5.
Zhang Y, Zhu Y, Chen Y, Wang Y, Liu B, Pan Y, et al.
iScience . 2024 Feb; 27(2):109011. PMID: 38357662
Loss of Protocadherin 9 (PCDH9) is associated with the metastasis and the prognosis of gastric cancer patients, while the molecular mechanism of PCDH9-impaired gastric cancer metastasis remains unclear. Here we...
6.
Ni C, Liu W, Zheng K, Guo S, Song B, Jing W, et al.
Int J Biol Sci . 2023 Apr; 19(6):1968-1982. PMID: 37063434
MLL-AFF4 fusion gene has been discovered in acute leukemia, whether AFF4 alone plays a role in tumor, especially pancreatic tumorigenesis, is still elusive. Increasing evidence suggests that cancer cells altered...
7.
Liu D, Dong C, Wang F, Liu W, Jin X, Qi S, et al.
Phytomedicine . 2023 Mar; 113:154732. PMID: 36933457
Background: New therapeutic approaches are required to improve the outcomes of lung cancer (LC), a leading cause of cancer-related deaths worldwide. Chinese herbal medicine formulae widely used in China provide...
8.
Huang W, Zhang J, Jin W, Yang J, Yu G, Shi H, et al.
Phytomedicine . 2022 Aug; 105:154361. PMID: 35963197
Background: Acute pancreatitis was a common acute abdominal disease characterized by pancreatic acinar cell death and inflammation. Endoplasmic reticulum autophagy (ER-phagy) coud maintain cell homeostasis by degrading redundant and disordered...
9.
Wu Q, Shi X, Pan Y, Liao X, Xu J, Gu X, et al.
Front Oncol . 2022 Jul; 12:874457. PMID: 35903688
Background: β-Elemene, an effective anticancer component isolated from the Chinese herbal medicine Rhizoma Zedoariae, has been proved to have therapeutic potential against multiple cancers by extensive clinical trials and experimental...
10.
Pan Y, Liao X, Yang L, Zhang C, Wang J, Zheng P, et al.
Front Pharmacol . 2022 Jul; 13:900128. PMID: 35847002
The extract of (Roxb.) Moon [Apocynaceae] (MTE) has shown a significant anti-cancer effect on hepatocellular carcinoma (HCC), but its mechanism remains unclear. In this study, we used transcriptomics methods to...