Guangfeng Geng
Overview
Explore the profile of Guangfeng Geng including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
198
Followers
0
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Recent Articles
1.
Liang J, Wan Y, Gao J, Zheng L, Wang J, Wu P, et al.
Nat Commun
. 2024 Jul;
15(1):5678.
PMID: 38971858
Inherited non-hemolytic anemia is a group of rare bone marrow disorders characterized by erythroid defects. Although concerted efforts have been made to explore the underlying pathogenetic mechanisms of these diseases,...
2.
Zhang X, Zhang Y, Geng G, Gao J, Tong J, Shi L, et al.
J Genet Genomics
. 2023 Aug;
50(8):624.
PMID: 37625883
No abstract available.
3.
Zhao T, Zhang J, Lei H, Meng Y, Cheng H, Zhao Y, et al.
EMBO J
. 2023 Jul;
42(16):e113258.
PMID: 37409632
Mitochondrial biogenesis is the process of generating new mitochondria to maintain cellular homeostasis. Here, we report that viruses exploit mitochondrial biogenesis to antagonize innate antiviral immunity. We found that nuclear...
4.
Chen L, Zhang Q, Meng Y, Zhao T, Mu C, Fu C, et al.
EMBO Rep
. 2023 Feb;
24(4):e54731.
PMID: 36847607
Ectopic lipid deposition and mitochondrial dysfunction are common etiologies of obesity and metabolic disorders. Excessive dietary uptake of saturated fatty acids (SFAs) causes mitochondrial dysfunction and metabolic disorders, while unsaturated...
5.
Zhang X, Zhang Y, Geng G, Gao J, Tong J, Shi L, et al.
J Genet Genomics
. 2023 Feb;
50(6):454-457.
PMID: 36773722
No abstract available.
6.
Xu C, He J, Wang H, Zhang Y, Wu J, Zhao L, et al.
Nat Immunol
. 2022 Jun;
23(7):1109-1120.
PMID: 35761081
Nonimmune cells can have immunomodulatory roles that contribute to healthy development. However, the molecular and cellular mechanisms underlying the immunomodulatory functions of erythroid cells during human ontogenesis remain elusive. Here,...
7.
Geng G, Liu J, Xu C, Pei Y, Chen L, Mu C, et al.
Elife
. 2021 May;
10.
PMID: 33942716
Erythropoietin (EPO) drives erythropoiesis and is secreted mainly by the kidney upon hypoxic or anemic stress. The paucity of EPO production in renal EPO-producing cells (REPs) causes renal anemia, one...
8.
Ma Y, Liu S, Gao J, Chen C, Zhang X, Yuan H, et al.
Dev Cell
. 2021 Jan;
56(4):478-493.e11.
PMID: 33476555
The human genome harbors 14,000 duplicated or retroposed pseudogenes. Given their functionality as regulatory RNAs and low conservation, we hypothesized that pseudogenes could shape human-specific phenotypes. To test this, we...
9.
Geng G, Xu C, Peng N, Li Y, Liu J, Wu J, et al.
Immunology
. 2021 Jan;
163(1):74-85.
PMID: 33421118
Dendritic cells (DCs) play an important role in linking innate and adaptive immunity. DCs can sense endogenous and exogenous antigens and present those antigens to T cells to induce an...
10.
Ma B, Cheng H, Mu C, Geng G, Zhao T, Luo Q, et al.
Nat Commun
. 2019 Mar;
10(1):1034.
PMID: 30833558
The interactions between tumor cells with their microenvironments, including hypoxia, acidosis and immune cells, lead to the tumor heterogeneity which promotes tumor progression. Here, we show that SIAH2-NRF1 axis remodels...