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Griet A Van Roey

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Citations 178
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Recent Articles
1.
Carpp L, Hyrien O, Fong Y, Benkeser D, Roels S, Stieh D, et al.
Nat Commun . 2024 Nov; 15(1):9785. PMID: 39532861
Assessment of immune correlates of severe COVID-19 has been hampered by the low numbers of severe cases in COVID-19 vaccine efficacy (VE) trials. We assess neutralizing and binding antibody levels...
2.
Bockstal V, Leyssen M, Heerwegh D, Spiessens B, Robinson C, Stoop J, et al.
NPJ Vaccines . 2022 Nov; 7(1):156. PMID: 36450746
Without clinical efficacy data, vaccine protective effect may be extrapolated from animals to humans using an immunologic marker that correlates with protection in animals. This immunobridging approach was used for...
3.
Fong Y, McDermott A, Benkeser D, Roels S, Stieh D, Vandebosch A, et al.
Nat Microbiol . 2022 Nov; 7(12):1996-2010. PMID: 36357712
Measuring immune correlates of disease acquisition and protection in the context of a clinical trial is a prerequisite for improved vaccine design. We analysed binding and neutralizing antibody measurements 4...
4.
Fong Y, McDermott A, Benkeser D, Roels S, Stieh D, Vandebosch A, et al.
medRxiv . 2022 Apr; PMID: 35441174
Anti-spike IgG binding antibody, anti-receptor binding domain IgG antibody, and pseudovirus neutralizing antibody measurements four weeks post-vaccination were assessed as correlates of risk of moderate to severe-critical COVID-19 outcomes through...
5.
Min J, Nayak J, Hulse K, Stevens W, Raju P, Huang J, et al.
J Allergy Clin Immunol . 2017 Jun; 140(6):1562-1571.e5. PMID: 28625807
Background: IgD is an enigmatic antibody isotype best known when coexpressed with IgM on naive B cells. However, increased soluble IgD (sIgD) levels and increased IgDIgM B-cell populations have been...
6.
Van Roey G, Vanison C, Wu J, Huang J, Suh L, Carter R, et al.
J Allergy Clin Immunol . 2016 Dec; 140(1):89-100.e2. PMID: 27979430
Background: Complement plays a major role in inflammatory diseases, but its involvement and mechanisms of activation in patients with chronic rhinosinusitis (CRS) are not known. Objectives: After earlier studies discovering...
7.
Arias M, Van Roey G, Tregoning J, Moutaftsi M, Coler R, Windish H, et al.
PLoS One . 2012 Jul; 7(7):e41144. PMID: 22829921
Successful vaccine development against HIV will likely require the induction of strong, long-lasting humoral and cellular immune responses in both the systemic and mucosal compartments. Based on the known immunological...
8.
Van Roey G, Arias M, Tregoning J, Rowe G, Shattock R
Eur J Immunol . 2011 Nov; 42(2):353-63. PMID: 22057556
The development of a successful vaccine against HIV is likely to require the induction of strong and long-lasting humoral immune responses at the mucosal portal of virus entry. Hence, the...