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Gregory J Tranah

Explore the profile of Gregory J Tranah including associated specialties, affiliations and a list of published articles. Areas
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Articles 102
Citations 2758
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Recent Articles
1.
Odden M, Li Y, Jotwani V, Dobrota S, Tan A, Cummings S, et al.
J Gerontol A Biol Sci Med Sci . 2024 Jul; 79(9). PMID: 39007867
Background: Mitochondrial dysfunction manifests in neurodegenerative diseases and other age-associated disorders. In this study, we examined variation in inherited mitochondrial DNA (mtDNA) sequences in Black and White participants from 2...
2.
Tranah G, Barnes H, Cawthon P, Coen P, Esser K, Hepple R, et al.
Aging Cell . 2024 Jun; 23(6):e14114. PMID: 38831629
Gene expression in skeletal muscle of older individuals may reflect compensatory adaptations in response to oxidative damage that preserve tissue integrity and maintain function. Identifying associations between oxidative stress response...
3.
Lukasiewicz C, Tranah G, Evans D, Coen P, Barnes H, Huo Z, et al.
Aging Cell . 2024 Jun; 23(6):e14115. PMID: 38831622
With aging skeletal muscle fibers undergo repeating cycles of denervation and reinnervation. In approximately the 8th decade of life reinnervation no longer keeps pace, resulting in the accumulation of persistently...
4.
Jotwani V, Thiessen-Philbrook H, Arking D, Yang S, McArthur E, Garg A, et al.
Am J Kidney Dis . 2024 Apr; 85(1):130-133. PMID: 38640995
No abstract available.
5.
Coen P, Huo Z, Tranah G, Barnes H, Zhang X, Wolff C, et al.
Aging Cell . 2024 Apr; 23(6):e14118. PMID: 38627910
Autophagy is essential for proteostasis, energetic balance, and cell defense and is a key pathway in aging. Identifying associations between autophagy gene expression patterns in skeletal muscle and physical performance...
6.
Jotwani V, Yang S, Thiessen-Philbrook H, Parikh C, Katz R, Tranah G, et al.
Hum Genet . 2024 Feb; 143(2):151-157. PMID: 38349571
Experimental models suggest an important role for mitochondrial dysfunction in the pathogenesis of chronic kidney disease (CKD) and acute kidney injury (AKI), but little is known regarding the impact of...
7.
Tranah G, Barnes H, Cawthon P, Coen P, Esser K, Hepple R, et al.
medRxiv . 2023 Nov; PMID: 37986804
Gene expression in skeletal muscle of older individuals may reflect compensatory adaptations in response to oxidative damage that preserve tissue integrity and maintain function. Identifying associations between oxidative stress response...
8.
Lukasiewicz C, Tranah G, Evans D, Coen P, Barnes H, Huo Z, et al.
medRxiv . 2023 Nov; PMID: 37961531
With aging skeletal muscle fibers undergo repeating cycles of denervation and reinnervation. In approximately the 8 decade of life reinnervation no longer keeps pace, resulting in the accumulation of persistently...
9.
Coen P, Huo Z, Tranah G, Barnes H, Cawthon P, Hepple R, et al.
medRxiv . 2023 Nov; PMID: 37961308
Autophagy is an essential component of proteostasis and a key pathway in aging. Identifying associations between autophagy gene expression patterns in skeletal muscle and physical performance outcomes would further our...
10.
Sheshadri A, Lai M, Hsu F, Bauer S, Chen S, Tse W, et al.
Kidney Med . 2023 Nov; 5(11):100721. PMID: 37915963
Rationale & Objective: In the Lifestyle Interventions and Independence for Elders (LIFE) trial, a structured exercise intervention slowed kidney function decline in sedentary older adults. Biomarkers of kidney health could...