Gregory D Bowden
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Explore the profile of Gregory D Bowden including associated specialties, affiliations and a list of published articles.
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17
Citations
87
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Recent Articles
1.
Spiller T, Donabauer K, Brooks A, Witek J, Bowden G, Scott P, et al.
Org Lett
. 2024 Jul;
26(30):6433-6437.
PMID: 39024514
This report describes a method for the photochemical Cu-mediated fluorination of aryl iodides with AgF via putative aryl radical (Ar•) intermediates. It involves irradiating an aryl iodide with UVB light...
2.
Bonanno F, Saw R, Bleher D, Papadopoulos I, Bowden G, Bjerregaard-Andersen K, et al.
ACS Omega
. 2024 Jun;
9(23):24774-24788.
PMID: 38882134
The development of positron emission tomography (PET) tracers capable of detecting α-synuclein (α-syn) aggregates in vivo would represent a breakthrough for advancing the understanding and enabling the early diagnosis of...
3.
Cheng K, Webb E, Bowden G, Wright J, Shao X, Sanford M, et al.
Org Lett
. 2024 Apr;
26(16):3419-3423.
PMID: 38630573
We present a photo- and Cu-mediated C cyanation of bench-stable (hetero)aryl thianthrenium salts via an aryl radical addition pathway. The thianthrenium substrates can be readily accessed via C-H functionalization, and...
4.
Webb E, Cheng K, Winton W, Klein B, Bowden G, Horikawa M, et al.
J Am Chem Soc
. 2024 Apr;
146(15):10581-10590.
PMID: 38580459
Positron emission tomography is a widely used imaging platform for studying physiological processes. Despite the proliferation of modern synthetic methodologies for radiolabeling, the optimization of these reactions still primarily relies...
5.
Bowden G, Stotz S, Dunkel G, Haas S, Kimmerle E, Schaller M, et al.
Bioconjug Chem
. 2024 Feb;
35(2):254-264.
PMID: 38308817
Preclinical models of neurological diseases and gene therapy are essential for neurobiological research. However, the evaluation of such models lacks reliable reporter systems for use with noninvasive imaging methods. Here,...
6.
Bowden G, Scott P, Boros E
ACS Cent Sci
. 2024 Jan;
9(12):2183-2195.
PMID: 38161375
Recent Food and Drug Administration (FDA) approval of diagnostic and therapeutic radiopharmaceuticals and concurrent miniaturization of particle accelerators leading to improved access has fueled interest in the development of chemical...
7.
Maciuba S, Bowden G, Stratton H, Wisniewski K, Schteingart C, Almagro J, et al.
MAbs
. 2023 Sep;
15(1):2254676.
PMID: 37698877
Prolactin (PRL) has recently been demonstrated to elicit female-selective nociceptor sensitization and increase pain-like behaviors in female animals. Here we report the discovery and characterization of first-in-class, humanized PRL neutralizing...
8.
Di Nanni A, Saw R, Battisti U, Bowden G, Boeckermann A, Bjerregaard-Andersen K, et al.
ACS Omega
. 2023 Sep;
8(34):31450-31467.
PMID: 37663501
A method to detect and quantify aggregated α-synuclein (αSYN) fibrils would drastically impact the current understanding of multiple neurodegenerative diseases, revolutionizing their diagnosis and treatment. Several efforts have produced promising...
9.
Di Nanni A, Saw R, Bowden G, Bidesi N, Bjerregaard-Andersen K, Korat S, et al.
Molecules
. 2023 May;
28(10).
PMID: 37241742
A technique to image α-synuclein (αSYN) fibrils in vivo is an unmet scientific and clinical need that would represent a transformative tool in the understanding, diagnosis, and treatment of various...
10.
Bone Relat R, Winder P, Bowden G, Guzman E, Peterson T, Pomponi S, et al.
Mar Drugs
. 2022 Apr;
20(4).
PMID: 35447913
sp. are apicomplexan parasites that cause significant morbidity and possible mortality in humans and valuable livestock. There are no drugs on the market that are effective in the population most...