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Gregory Crosby

Explore the profile of Gregory Crosby including associated specialties, affiliations and a list of published articles. Areas
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Articles 74
Citations 2208
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Recent Articles
1.
Yin Z, Leonard A, Porto C, Xie Z, Silveira S, Culley D, et al.
J Neuroinflammation . 2024 Dec; 21(1):323. PMID: 39696348
Background: Microglia, the resident immune cells of the brain, play a crucial role in maintaining homeostasis in the central nervous system (CNS). However, they can also contribute to neurodegeneration through...
2.
Oren R, Grasfield R, Friese M, Chibnik L, Chi J, Groff M, et al.
J Clin Med . 2023 Oct; 12(19). PMID: 37834915
Surgery is a major challenge for the immune system, but little is known about the immune response of geriatric patients to surgery. We therefore investigated the impact of surgery on...
3.
Friese M, Gujral T, Palanisamy A, Hemmer B, Culley D, Crosby G
Front Aging Neurosci . 2023 Jun; 15:1060186. PMID: 37261265
Introduction: The development and maintenance of neural circuits is highly sensitive to neural activity. General anesthetics have profound effects on neural activity and, as such, there is concern that these...
4.
Lu J, Liang F, Bai P, Liu C, Xu M, Sun Z, et al.
Alzheimers Dement . 2023 May; 19(9):4110-4126. PMID: 37249148
Introduction: Blood phosphorylated tau at threonine 217 (tau-PT217) is a newly established biomarker for Alzheimer's disease and postoperative delirium in patients. However, the mechanisms and consequences of acute changes in...
5.
Oren R, Kim E, Leonard A, Rosner B, Chibnik L, Das S, et al.
Sci Rep . 2023 May; 13(1):7431. PMID: 37156856
Delirium is an acute confusional state and a common postoperative morbidity. Prevalent in older adults, delirium occurs at other ages but it is unclear whether the pathophysiology and biomarkers for...
6.
Vasunilashorn S, Lunardi N, Newman J, Crosby G, Acker L, Abel T, et al.
Alzheimers Dement . 2023 Feb; 19(5):2150-2174. PMID: 36799408
Delirium is a common, morbid, and costly syndrome that is closely linked to Alzheimer's disease (AD) and AD-related dementias (ADRD) as a risk factor and outcome. Human studies of delirium...
7.
Zhang C, Han Y, Liu X, Tan H, Dong Y, Zhang Y, et al.
Ann Surg . 2022 Jul; 277(6):e1387-e1396. PMID: 35848747
Objective: To determine the association between olfactory function and cognition in patients and rodents. Background: Perioperative neurocognitive disorders include delayed neurocognitive recovery (dNCR). The contribution of olfactory function to dNCR...
8.
Crosby G, Vutskits L
Anesth Analg . 2021 Oct; 133(5):1138-1139. PMID: 34673724
No abstract available.
9.
Susano M, Dias M, Seixas F, Vide S, Grasfield R, Abelha F, et al.
Anesth Analg . 2020 Oct; 132(3):846-855. PMID: 33002925
Background: Postoperative delirium is common among older patients and preoperative identification of high-risk patients is widely recommended. The aim of this study was to assess whether preoperative cognitive performance using...
10.
Susano M, Grasfield R, Friese M, Rosner B, Crosby G, Bader A, et al.
Anesthesiology . 2020 Sep; 133(6):1184-1191. PMID: 32898243
Background: Frailty and cognitive impairment are associated with postoperative delirium, but are rarely assessed preoperatively. The study was designed to test the hypothesis that preoperative screening for frailty or cognitive...