Graeme Alexander
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Explore the profile of Graeme Alexander including associated specialties, affiliations and a list of published articles.
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46
Citations
3078
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Recent Articles
1.
Cullen K, Jones M, Pockett R, Burton A, Cross T, Rowe I, et al.
BMJ Open Gastroenterol
. 2023 Feb;
10(1).
PMID: 36810207
Objective: Hepatocellular carcinoma (HCC) incidence in the UK trebled between 1997 and 2017. With increasing numbers requiring treatment, understanding the likely impact on healthcare budgets can inform service planning and...
2.
Shribman S, Marjot T, Sharif A, Vimalesvaran S, Ala A, Alexander G, et al.
Lancet Gastroenterol Hepatol
. 2022 Apr;
7(6):560-575.
PMID: 35429442
Wilson's disease is an autosomal-recessive disorder of copper metabolism with hepatic, neurological, psychiatric, ophthalmological, haematological, renal, and rheumatological manifestations. Making a diagnosis can be challenging given that no single test...
3.
Valencia A, Vergara C, Thio C, Vince N, Douillard V, Grifoni A, et al.
Am J Hum Genet
. 2022 Jan;
109(2):299-310.
PMID: 35090584
Spontaneous clearance of acute hepatitis C virus (HCV) infection is associated with single nucleotide polymorphisms (SNPs) on the MHC class II. We fine-mapped the MHC region in European (n =...
4.
Burton A, Balachandrakumar V, Driver R, Tataru D, Paley L, Marshall A, et al.
Br J Cancer
. 2021 Nov;
126(5):804-814.
PMID: 34837073
Background: Hepatocellular carcinoma (HCC) incidence, management and survival across England were examined to determine if geographical inequalities exist. Method: 15,468 HCC cases diagnosed 2010-2016 were included. Age-standardised incidence rates, net...
5.
Burton A, Tataru D, Driver R, Bird T, Huws D, Wallace D, et al.
JHEP Rep
. 2021 Mar;
3(2):100232.
PMID: 33748727
Background & Aims: The incidence of primary liver cancer (PLC) is increasing in Western Europe. To understand trends over time and the current burden in the UK, a detailed analysis...
6.
Williams R, Alessi C, Alexander G, Allison M, Aspinall R, Batterham R, et al.
Lancet
. 2021 Mar;
397(10286):1770-1780.
PMID: 33714360
This Review, in addressing the unacceptably high mortality of patients with liver disease admitted to acute hospitals, reinforces the need for integrated clinical services. The masterplan described is based on...
7.
Vergara C, Duggal P, Thio C, Valencia A, OBrien T, Latanich R, et al.
Genes Immun
. 2020 Nov;
21(6-8):420.
PMID: 33230236
No abstract available.
8.
Vergara C, Valencia A, Thio C, Goedert J, Mangia A, Piazzolla V, et al.
J Infect Dis
. 2020 Oct;
223(12):2090-2098.
PMID: 33119750
Background: Spontaneous clearance of acute hepatitis C virus (HCV) infection is more common in women than in men, independent of known risk factors. Methods: To identify sex-specific genetic loci, we...
9.
Vergara C, Duggal P, Thio C, Valencia A, OBrien T, Latanich R, et al.
Genes Immun
. 2020 Oct;
21(5):348-359.
PMID: 33116245
Clearance of acute infection with hepatitis C virus (HCV) is associated with the chr19q13.13 region containing the rs368234815 (TT/ΔG) polymorphism. We fine-mapped this region to detect possible causal variants that...
10.
Beebeejaun K, Amin-Chowdhury Z, Letley L, Kara E, Mahange B, Harrington K, et al.
J Viral Hepat
. 2020 Sep;
28(1):72-79.
PMID: 32926589
Around 200,000 people live with chronic hepatitis B in England. Despite national guidance on identification and management of cases and their close contacts, testing rates of close contacts is as...