Gordon Watson
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Explore the profile of Gordon Watson including associated specialties, affiliations and a list of published articles.
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29
Citations
164
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Recent Articles
11.
Watson G, Davies J, Wood H, Cocks A
PLoS One
. 2018 Jun;
13(6):e0199516.
PMID: 29953461
Several million gastropods are collected each year for the marine ornamental trade to graze on algae detrimental to aquarium species, however, little is known about popular species' suitability to perform...
12.
Makarova A, Pasta S, Watson G, Shackleton C, Epstein Jr E
J Steroid Biochem Mol Biol
. 2017 Mar;
171:187-194.
PMID: 28330720
The lower risk of some internal cancers at lower latitudes has been linked to greater sun exposure and consequent higher levels of ultraviolet radiation (UVR)-produced vitamin D (D). To separate...
13.
Pasta S, Akhile O, Tabron D, Ting F, Shackleton C, Watson G
Mol Genet Metab Rep
. 2015 Sep;
4:92-98.
PMID: 26347274
Smith Lemli Opitz syndrome (SLOS) is an inherited malformation and mental retardation metabolic disorder with no cure. Mutations in the last enzyme of the cholesterol biosynthetic pathway, 7-dehydrocholesterol reductase (DHCR7),...
14.
Xue Y, Ying L, Horst R, Watson G, Goltzman D
J Invest Dermatol
. 2015 Jul;
135(12):3125-3132.
PMID: 26214382
Cutaneous exposure to UVB irradiation is an important source of vitamin D. Here, we examined sex-specific differences in cutaneous vitamin D production in mice. Both male and female mice on...
15.
Sharma V, Witkowski A, Witkowska H, Dykstra A, Simonsen J, Nelbach L, et al.
Arterioscler Thromb Vasc Biol
. 2014 Aug;
34(10):2254-60.
PMID: 25127531
Objective: Apolipoprotein A-V (apoA-V) is a low-abundance plasma protein that modulates triacylglycerol homeostasis. Gene transfer studies were undertaken in apoa5 (-/-) mice to define the mechanism underlying the correlation between...
16.
Ying L, Matabosch X, Serra M, Watson B, Shackleton C, Watson G
Mol Genet Metab Rep
. 2014 Jul;
1:103-113.
PMID: 25024934
Smith-Lemli-Opitz syndrome (SLOS) is an inborn error of cholesterol synthesis resulting from a defect in 7-dehydrocholesterol reductase (DHCR7), the enzyme that produces cholesterol from its immediate precursor 7-dehydrocholesterol. Current therapy...
17.
Sharma V, Beckstead J, Simonsen J, Nelbach L, Watson G, Forte T, et al.
Arterioscler Thromb Vasc Biol
. 2013 Jan;
33(3):474-80.
PMID: 23329134
Objective: Apolipoprotein (apo) A-V is a low abundance protein with a profound influence on plasma triacylglycerol levels. In human populations, single nucleotide polymorphisms and mutations in APOA5 positively correlate with...
18.
Ali K, Raja M, Watson G, Coombes L, Heffernan E
J Dent Educ
. 2012 Apr;
76(4):487-94.
PMID: 22473561
The significance of the educational environment in health professions academic institutions, increasingly recognized on a global scale, is fundamental to effective student learning. This study was carried out to evaluate...
19.
Serra M, Matabosch X, Ying L, Watson G, Shackleton C
J Steroid Biochem Mol Biol
. 2010 Sep;
122(5):318-25.
PMID: 20804844
Our recent studies have focused on cholesterol synthesis in mouse models for 7-dehydrosterolreductase (DHCR7) deficiency, also known as Smith-Lemli-Opitz syndrome. Investigations of such mutants have relied on tissue and blood...
20.
Matabosch X, Ying L, Serra M, Wassif C, Porter F, Shackleton C, et al.
J Steroid Biochem Mol Biol
. 2010 Aug;
122(5):303-9.
PMID: 20800683
Smith-Lemli-Opitz syndrome (SLOS) is caused by deficiency in the terminal step of cholesterol biosynthesis: the conversion of 7-dehydrocholesterol (7DHC) to cholesterol (C), catalyzed by 7-dehydrocholesterol reductase (DHCR7). This disorder exhibits...