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Gopal Pawar

Explore the profile of Gopal Pawar including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 105
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Recent Articles
1.
Pawar G, Wu F, Zhao L, Fang L, Burckart G, Feng K, et al.
AAPS J . 2023 Jun; 25(4):67. PMID: 37386339
This study investigated the impact of gastro-intestinal fluid volume and bile salt (BS) concentration on the dissolution of carbamazepine (CBZ) immediate release (IR) 100 mg tablets and to integrate these...
2.
Goelen J, Alexander B, Wijesinghe H, Evans E, Pawar G, Horniblow R, et al.
Pharmaceutics . 2021 Oct; 13(10). PMID: 34684022
Previous studies have used magnetic resonance imaging (MRI) to quantify the fluid in the stomach and small intestine of children, and the stomach, small intestine and colon of adults. This...
3.
Pawar G, Wu F, Zhao L, Fang L, Burckart G, Feng K, et al.
AAPS J . 2021 Apr; 23(3):57. PMID: 33884497
Generally, bioequivalence (BE) studies of drug products for pediatric patients are conducted in adults due to ethical reasons. Given the lack of direct BE assessment in pediatric populations, the aim...
4.
Pawar G, Papadatou-Soulou E, Mason J, Muhammed R, Watson A, Cotter C, et al.
Eur J Pharm Biopharm . 2020 Dec; 158:156-165. PMID: 33259897
Fundamental knowledge about the composition of intestinal fluids in paediatric populations is currently unavailable. This study aimed to characterise gastric and intestinal fluid from paediatric populations. Gastric and intestinal fluid...
5.
Pawar G, Madden J, Ebbrell D, Firman J, Cronin M
Front Pharmacol . 2019 Jun; 10:561. PMID: 31244651
A plethora of databases exist online that can assist in chemical or drug safety assessment. However, a systematic review and grouping of databases, based on purpose and information content, consolidated...
6.
Pletz J, Enoch S, Jais D, Mellor C, Pawar G, Firman J, et al.
Expert Opin Drug Metab Toxicol . 2018 Oct; 14(12):1225-1253. PMID: 30345815
The kidney is a major target for toxicity elicited by pharmaceuticals and environmental pollutants. Standard testing which often does not investigate underlying mechanisms has proven not to be an adequate...
7.
Pawar G, Abdallah M, de Saa E, Harrad S
J Expo Sci Environ Epidemiol . 2016 Jan; 27(1):100-105. PMID: 26732374
Despite extensive literature on their potential adverse health effects, there is a lack of information on human dermal exposure to organic flame retardant chemicals (FRs). This study applies an in...
8.
Abdallah M, Pawar G, Harrad S
Toxicol Appl Pharmacol . 2015 Dec; 291:28-37. PMID: 26712466
Tris-2-chloroethyl phosphate (TCEP), tris (1-chloro-2-propyl) phosphate (TCIPP) and tris-1,3-dichloropropyl phosphate (TDCIPP) are organophosphate flame retardants (PFRs) widely applied in a plethora of consumer products despite their carcinogenic potential. Human dermal...
9.
Abdallah M, Pawar G, Harrad S
Environ Sci Technol . 2015 Aug; 49(18):10976-83. PMID: 26301594
Human dermal absorption of eight mono- to deca-brominated diphenyl ethers (PBDEs) was investigated for the first time using EPISKIN human skin equivalent tissue. Using a standard in vitro protocol, EPISKIN...
10.
Abdallah M, Pawar G, Harrad S
Environ Int . 2015 Aug; 84:64-70. PMID: 26232142
Ethical and technical difficulties inherent to studies in human tissues are impeding assessment of the dermal bioavailability of brominated flame retardants (BFRs). This is further complicated by increasing restrictions on...