Gopal L Khatik
Overview
Explore the profile of Gopal L Khatik including associated specialties, affiliations and a list of published articles.
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Articles
42
Citations
240
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Recent Articles
1.
Kumar H, Datusalia A, Kumar A, Khatik G
J Biomol Struct Dyn
. 2025 Mar;
:1-14.
PMID: 40035614
One of the most common causes of dementia in older adults is Alzheimer's disease (AD). Numerous mechanisms, including acetylcholine breakdown, amyloid beta buildup, neurofibrillary tangle accumulation, and inflammation, are involved...
2.
Kumar H, Datusalia A, Kumar A, Khatik G
Cent Nerv Syst Agents Med Chem
. 2024 Oct;
PMID: 39449347
Aim: We aimed to conduct in silico screening of the potential phytoconstituent from a natural product database to find SIRT2 inhibitors. Background: Alzheimer's disease (AD) is the most prevalent type...
3.
Khola S, Kumar S, Bhanwala N, Khatik G
Curr Top Med Chem
. 2024 Sep;
24(27):2362-2376.
PMID: 39297467
Tuberculosis is one of the deadly infectious diseases that has resurfaced in multiple/ extensively resistant variants (MDR/XDR), threatening humankind. Today's world has a higher prevalence of tuberculosis (TB) than it...
4.
Choudhary N, Khatik G, Sharma R, Khurana N, Lobo R, Bhatt S, et al.
3 Biotech
. 2024 Aug;
14(9):206.
PMID: 39170771
[This retracts the article DOI: 10.1007/s13205-021-02811-x.].
5.
Kumar M, Sharma A, Datusalia A, Khatik G
Med Chem
. 2024 May;
20(8):781-798.
PMID: 38726789
Alzheimer's disease (AD) is a neurodegenerative disease leading to dementia because of complex phathomechanisms like amyloid β (Aβ) aggregation, tau aggregates, and neurofibrillary tangles. Peroxisome proliferator-activated receptor (PPAR) agonists have...
6.
Kumar H, Datusalia A, Khatik G
In Silico Pharmacol
. 2024 Feb;
12(1):13.
PMID: 38370859
Graphical Abstract: Supplementary Information: The online version contains supplementary material available at 10.1007/s40203-024-00189-1.
7.
Agarwal D, Kumar S, Ambatwar R, Bhanwala N, Chandrakar L, Khatik G
Cent Nerv Syst Agents Med Chem
. 2024 Jan;
24(2):219-242.
PMID: 38288823
Aims: In this work, we aimed to acquire the best potential small molecule for Alzheimer's disease (AD) treatment using different models in Biovia Discovery Studio to identify new potential inhibitors...
8.
Chandrakar L, Ambatwar R, Khatik G
Curr Top Med Chem
. 2023 Dec;
24(2):157-178.
PMID: 38037999
Cellular senescence, an eternal condition of cell cycle arrest due to cellular stressors, is a sign of aging. Senescent cells (SCs) build up in tissues as they age, impairing their...
9.
Agarwal D, Malik J, Bhanwala N, Ambatwar R, Kumar S, Chandrakar L, et al.
J Biomol Struct Dyn
. 2023 Oct;
42(22):12304-12316.
PMID: 37861402
Alzheimer's disease (AD) is a deteriorating neural disorder, and currently, available drugs are ineffective in its treatment. (Amla) is widely recognised in the Indian medicinal system for ameliorative effects in...
10.
Kumar S, Mahajan A, Ambatwar R, Khatik G
Curr Med Chem
. 2023 Oct;
31(37):6032-6062.
PMID: 37861025
Alzheimer's disease (AD) is a neurodegenerative disease and one of the leading causes of progressive dementia, affecting 50 million people worldwide. Many pathogenic processes, including amyloid β aggregation, tau hyperphosphorylation,...