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Golareh Agha

Explore the profile of Golareh Agha including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 1136
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Recent Articles
1.
Huan T, Joehanes R, Song C, Peng F, Guo Y, Mendelson M, et al.
Nat Commun . 2019 Sep; 10(1):4267. PMID: 31537805
Identifying methylation quantitative trait loci (meQTLs) and integrating them with disease-associated variants from genome-wide association studies (GWAS) may illuminate functional mechanisms underlying genetic variant-disease associations. Here, we perform GWAS of...
2.
Agha G, Mendelson M, Ward-Caviness C, Joehanes R, Huan T, Gondalia R, et al.
Circulation . 2019 Aug; 140(8):645-657. PMID: 31424985
Background: DNA methylation is implicated in coronary heart disease (CHD), but current evidence is based on small, cross-sectional studies. We examined blood DNA methylation in relation to incident CHD across...
3.
Agha G, Kezios K, Baccarelli A, Bowman F, Rauh V, Susser E, et al.
Ann Epidemiol . 2019 May; 35:48-52.e2. PMID: 31060895
Purpose: Cognitive development during adolescence affects health long term. We investigated whether level of and change in language-based cognition during adolescence are associated with cognitive performance in midlife. Methods: Participants...
4.
Grau-Perez M, Agha G, Pang Y, Bermudez J, Tellez-Plaza M
Curr Environ Health Rep . 2019 Feb; 6(1):38-51. PMID: 30773605
Purpose Of Review: Epigenetic modifications are environmentally responsive and may play a mechanistic role in the development of disease. Mendelian randomization uses genetic variation to assess the causal effect of...
5.
Ward-Caviness C, Agha G, Chen B, Pfeiffer L, Wilson R, Wolf P, et al.
Clin Epigenetics . 2018 Dec; 10(1):161. PMID: 30587240
Background: Most research into myocardial infarctions (MIs) have focused on preventative efforts. For survivors, the occurrence of an MI represents a major clinical event that can have long-lasting consequences. There...
6.
Huang J, Cardenas A, Colicino E, Schooling C, Rifas-Shiman S, Agha G, et al.
Epigenetics . 2018 Nov; 13(10-11):1072-1087. PMID: 30412002
Obesity is associated with higher cardio-metabolic risk even in childhood and adolescence; whether this association is mediated by epigenetic mechanisms remains unclear. We examined the extent to which mid-childhood body...
7.
Gilman S, Huang Y, Jimenez M, Agha G, Chu S, Eaton C, et al.
Int J Epidemiol . 2018 Oct; 48(1):98-107. PMID: 30277525
Background: Early exposure to socioeconomic disadvantage is associated with obesity. Here we investigated how early, and conducted mediation analyses to identify behavioural factors in adulthood that could explain why. Methods:...
8.
Peng C, Den Dekker M, Cardenas A, Rifas-Shiman S, Gibson H, Agha G, et al.
Environ Health Perspect . 2018 Sep; 126(9):97006. PMID: 30226399
Background: Epigenetic variability is hypothesized as a regulatory pathway through which prenatal exposures may influence child development and health. Objective: We sought to examine the associations of residential proximity to...
9.
Chu S, Loucks E, Kelsey K, Gilman S, Agha G, Eaton C, et al.
Epigenomics . 2018 Jun; 10(6):707-722. PMID: 29888956
Aim: The objective of this study was to identify potential epigenetic mediating pathways linking early life social disadvantage (ELSD) to adulthood BMI. Methods: Sex-specific epigenome-wide two-stage mediation analyses were conducted...
10.
Aslibekyan S, Agha G, Colicino E, Do A, Lahti J, Ligthart S, et al.
JAMA Cardiol . 2018 Apr; 3(6):463-472. PMID: 29617535
Importance: Tumor necrosis factor α (TNF-α) is a proinflammatory cytokine with manifold consequences for mammalian pathophysiology, including cardiovascular disease. A deeper understanding of TNF-α biology may enhance treatment precision. Objective:...