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Gokce A Toruner

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Articles 57
Citations 450
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Recent Articles
1.
Wei Q, Hu S, Loghavi S, Toruner G, Ravandi-Kashani F, Tang Z, et al.
Am J Hematol . 2025 Jan; 100(3):417-426. PMID: 39871121
Chromoanagenesis (CAG) encompasses a spectrum of catastrophic genomic events, including chromothripsis, chromoanasynthesis, and chromoplexy. We studied CAG in 410 patients with a diagnosis of acute myeloid leukemia (AML), 292 newly...
2.
Wei Q, Hu S, Xu J, Loghavi S, Daver N, Toruner G, et al.
Cancers (Basel) . 2025 Jan; 16(24. PMID: 39766092
partial tandem duplication (PTD) involves intragenic duplications and has been associated with poorer prognosis. In this study, we evaluated PTD in 1277 patients with hematological malignancies using optical genome mapping...
3.
Yang R, Alvarez H, Lucas A, Roy-Chowdhuri S, Rashid A, Chen H, et al.
Cancer Genet . 2024 Dec; 290-291():44-50. PMID: 39700818
Impairment of DNA mismatch repair function in neoplasms can be assessed by DNA-based methods to assess for high microsatellite instability (MSI-High) or immunohistochemical (IHC) analysis to assess for deficiency of...
4.
Tang Z, Wang W, Toruner G, Hu S, Fang H, Xu J, et al.
Genes (Basel) . 2024 Nov; 15(11). PMID: 39596557
fusion is mostly derived from a reciprocal translocation t(9;22)(q34.1;q11.2) and is rarely caused by insertion. Various methods have been used for the detection of t(9;22)/, such as G-banded chromosomal analysis,...
5.
Ozkizilkaya H, Vinocha A, Dono A, Ogunbona O, Toruner G, Aung P, et al.
Cancers (Basel) . 2024 Oct; 16(19). PMID: 39409918
Background: Homozygous cyclin-dependent kinase inhibitor 2A/B (CDKN2A/B) loss is one of the parameters that support the designation of meningiomas as Central Nervous System (CNS) WHO grade 3 tumors. Evaluation of...
6.
Loghavi S, Wei Q, Ravandi F, Quesada A, Routbort M, Hu S, et al.
Am J Hematol . 2024 Jul; 99(10):1959-1968. PMID: 39016111
Cytogenomic characterization is crucial for the classification and risk stratification of acute myeloid leukemia (AML), thereby facilitating therapeutic decision-making. We examined the clinical utility of optical genome mapping (OGM) in...
7.
Sameeta F, Fang H, Wang W, Tang Z, Wang S, Toruner G, et al.
Am J Hematol . 2024 Mar; 99(9):1827-1829. PMID: 38440855
No abstract available.
8.
Quesada A, Hu S, Li S, Toruner G, Wei Q, Loghavi S, et al.
Hum Pathol . 2024 Feb; 144:71-76. PMID: 38301962
Optical genome mapping (OGM) is a new DNA-based technology which provides comprehensive examination of the entire genome. We report two patients who presented with splenomegaly and leukocytosis with lymphocytosis including...
9.
Vanjari N, Tang G, Toruner G, Wang W, Thakral B, Zhao M, et al.
Genes (Basel) . 2023 Dec; 14(12). PMID: 38137010
We report a case of myeloproliferative neoplasm, not otherwise specified (MPN-NOS)-transformed AML with rearrangement. Chromosomal analysis indicated a simple abnormal karyotype 46,XY,t(7;17)(q21;q24),t(9;22)(p24;q11.2). Fluorescence in situ hybridization (FISH) using a BCR/ABL1/ASS1...
10.
Tang G, Wu Y, Lin P, Toruner G, Hu S, Li S, et al.
Cancers (Basel) . 2023 Dec; 15(23). PMID: 38067393
The aim of this study was to examine the cytogenetic profiles of plasma cell neoplasms (PCNs) at various disease stages, encompassing 1087 patients with monoclonal gammopathy of undetermined significance (MGUS),...