Go Woon Kim
Overview
Explore the profile of Go Woon Kim including associated specialties, affiliations and a list of published articles.
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Articles
42
Citations
691
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Recent Articles
11.
Kim G, Lee D, Jeon Y, Yoo J, Kim S, Lee S, et al.
Int J Mol Sci
. 2021 Feb;
22(4).
PMID: 33567690
The significance of glutamine in cancer metabolism has been extensively studied. Cancer cells consume an excessive amount of glutamine to facilitate rapid proliferation. Thus, glutamine depletion occurs in various cancer...
12.
Lee D, Kim G, Yoo J, Lee S, Jeon Y, Kim S, et al.
Cell Death Dis
. 2021 Jan;
12(1):89.
PMID: 33462212
Glioblastoma is the most lethal brain tumor and its pathogenesis remains incompletely understood. KDM4C is a histone H3K9 demethylase that contributes to epigenetic regulation of both oncogene and tumor suppressor...
13.
Cho H, Lee S, Jeon Y, Lee D, Kim G, Yoo J, et al.
Int J Mol Sci
. 2020 Sep;
21(18).
PMID: 32961679
Overexpression of histone deacetylase 6 (HDAC6) and bromodomain-containing protein 4 (BRD4) is related to aggressiveness of head and neck squamous carcinoma (HNSCC). Based on studies that HDAC6 and BRD4 are...
14.
Yi S, Kim G, Yoo J, Han J, Kwon S
Int J Mol Sci
. 2020 Aug;
21(17).
PMID: 32825184
Cisplatin is the most frequently used agent for chemotherapy against cervical cancer. However, recurrent use of cisplatin induces resistance, representing a major hurdle in the treatment of cervical cancer. Our...
15.
Kim G, Yoo J, Won H, Yeon S, Lee S, Lee D, et al.
Leuk Res
. 2020 Jun;
95:106398.
PMID: 32512378
Multiple Myeloma (MM) is a hematological malignancy of plasma cells. Although advanced therapies have elevated MM survival rate, MM eventually relapses. Relapsed/refractory MM (R/R MM) cells gain resistance to previously...
16.
Yoo J, Jeon Y, Cho H, Lee S, Kim G, Lee D, et al.
Cancers (Basel)
. 2020 May;
12(5).
PMID: 32354028
Lysine-specific histone demethylase 3 (KDM3) subfamily proteins are H3K9me2/me1 histone demethylases that promote gene expression. The KDM3 subfamily primarily consists of four proteins (KDM3A-D). All four proteins contain the catalytic...
17.
Yi S, Lee D, Kim G, Ryu H, Park J, Lee J, et al.
Cell Death Differ
. 2020 Mar;
27(9):2537-2551.
PMID: 32203172
E6 oncoprotein derived from high-risk human papillomavirus (HPV) drives the development of cervical cancer through p53 degradation. Because cervical cancer therapies to inactivate HPV or E6 protein are not available,...
18.
Park S, Kim G, Kwon S, Lee J
FEBS J
. 2020 Jan;
287(14):2891-2902.
PMID: 31967712
Histone modifications affect transcription by changing the chromatin structure. In particular, histone H3 lysine 4 trimethylation (H3K4me3) is one of the most recognized epigenetic marks of active transcription. While many...
19.
Lee D, Kim G, Jeon Y, Yoo J, Lee S, Kwon S
FASEB J
. 2020 Jan;
34(3):3461-3484.
PMID: 31961018
The KDM4 subfamily H3K9 histone demethylases are epigenetic regulators that control chromatin structure and gene expression by demethylating histone H3K9, H3K36, and H1.4K26. The KDM4 subfamily mainly consists of four...
20.
Kim G, Lee D, Yeon S, Jeon Y, Yoo J, Lee S, et al.
Anticancer Res
. 2019 Dec;
39(12):6731-6741.
PMID: 31810938
Background/aim: Histone deacetylase 6 (HDAC6) is considered as one of the most promising targets in drug development for cancer therapy. Drug resistance is a major cause of treatment failure in...