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Gloria Giovannini

Explore the profile of Gloria Giovannini including associated specialties, affiliations and a list of published articles. Areas
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Articles 21
Citations 1933
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Recent Articles
1.
Bedke T, Iannitti R, De Luca A, Giovannini G, Fallarino F, Berges C, et al.
Immunol Cell Biol . 2014 May; 92(8):659-70. PMID: 24820384
Unlike induced Foxp3(+) regulatory T cells (Foxp3(+) iTreg) that have been shown to play an essential role in the development of protective immunity to the ubiquitous mold Aspergillus fumigatus, type-(1)-regulatory...
2.
Zelante T, Iannitti R, Cunha C, De Luca A, Giovannini G, Pieraccini G, et al.
Immunity . 2013 Aug; 39(2):372-85. PMID: 23973224
Endogenous tryptophan (Trp) metabolites have an important role in mammalian gut immune homeostasis, yet the potential contribution of Trp metabolites from resident microbiota has never been addressed experimentally. Here, we...
3.
De Luca A, Carvalho A, Cunha C, Iannitti R, Pitzurra L, Giovannini G, et al.
PLoS Pathog . 2013 Jul; 9(7):e1003486. PMID: 23853597
The ability to tolerate Candida albicans, a human commensal of the gastrointestinal tract and vagina, implicates that host defense mechanisms of resistance and tolerance cooperate to limit fungal burden and...
4.
Bezerra A, Simoes J, Lee W, Rung J, Weil T, Gut I, et al.
Proc Natl Acad Sci U S A . 2013 Jun; 110(27):11079-84. PMID: 23776239
Many fungi restructured their proteomes through incorporation of serine (Ser) at thousands of protein sites coded by the leucine (Leu) CUG codon. How these fungi survived this potentially lethal genetic...
5.
Rizzetto L, Giovannini G, Bromley M, Bowyer P, Romani L, Cavalieri D
PLoS One . 2013 Feb; 8(2):e56651. PMID: 23441211
For over a century microbiologists and immunologist have categorized microorganisms as pathogenic or non-pathogenic species or genera. This definition, clearly relevant at the strain and species level for most bacteria,...
6.
Iannitti R, Carvalho A, Cunha C, De Luca A, Giovannini G, Casagrande A, et al.
Am J Respir Crit Care Med . 2013 Jan; 187(6):609-20. PMID: 23306541
Rationale: Mutations in the cystic fibrosis (CF) transmembrane conductance regulator affect the innate epithelial immune function of the lung, resulting in exaggerated and ineffective airway inflammation that fails to eradicate...
7.
Carvalho A, Cunha C, Iannitti R, De Luca A, Giovannini G, Bistoni F, et al.
Ann N Y Acad Sci . 2012 Dec; 1273:52-9. PMID: 23230837
Aspergillosis includes a spectrum of diseases caused by different Aspergillus spp. New insights into the cellular and molecular mechanisms of resistance and immune tolerance to the fungus in infection and...
8.
Carvalho A, Giovannini G, De Luca A, DAngelo C, Casagrande A, Iannitti R, et al.
Cell Mol Immunol . 2012 May; 9(3):276-86. PMID: 22543832
The recognition of β-glucans by dectin-1 has been shown to mediate cell activation, cytokine production and a variety of antifungal responses. Here, we report that the functional activity of dectin-1...
9.
De Luca A, Iannitti R, Bozza S, Beau R, Casagrande A, DAngelo C, et al.
J Clin Invest . 2012 Apr; 122(5):1816-31. PMID: 22523066
Aspergillus fumigatus is a model fungal pathogen and a common cause of infection in individuals with the primary immunodeficiency chronic granulomatous disease (CGD). Although primarily considered a deficiency of innate...
10.
Cunha C, Giovannini G, Pierini A, Bell A, Sorci G, Riuzzi F, et al.
PLoS One . 2011 Nov; 6(11):e27962. PMID: 22114731
Invasive aspergillosis (IA) is a major threat to the successful outcome of hematopoietic stem cell transplantation (HSCT), although individual risk varies considerably. Recent evidence has established a pivotal role for...