Glenn E Croston
Overview
Explore the profile of Glenn E Croston including associated specialties, affiliations and a list of published articles.
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8
Citations
81
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Recent Articles
1.
Schmidt W, Cortes-Puch I, McReynolds C, Croston G, Hwang S, Yang J, et al.
Clin Transl Sci
. 2024 Sep;
17(9):e70033.
PMID: 39300734
Chronic pain represents a significant unmet medical need, affecting one-fifth of the U.S. population. EC5026 is a small molecule inhibitor of the enzyme soluble epoxide hydrolase (sEH) which is being...
2.
Iampietro C, Brossa A, Canosa S, Tritta S, Croston G, Reinheimer T, et al.
Int J Mol Sci
. 2022 Feb;
23(3).
PMID: 35163699
Endometrial mesenchymal stromal cells (E-MSCs) extensively contribute to the establishment and progression of endometrial ectopic lesions through formation of the stromal vascular tissue, and support to its growth and vascularization....
3.
Barabutis N, Marinova M, Solopov P, Uddin M, Croston G, Reinheimer T, et al.
J Pharmacol Exp Ther
. 2020 Sep;
375(2):286-295.
PMID: 32943478
Sepsis and septic shock are among the most common causes of death in the intensive care unit; advanced therapeutic approaches are thus urgently needed. Vascular hyperpermeability represents a major manifestation...
4.
Koechling W, Plaksin D, Croston G, Jeppesen J, Macklon K, Andersen C
Endocr Connect
. 2017 Apr;
6(5):297-305.
PMID: 28450423
Recombinant FSH proteins are important therapeutic agents for the treatment of infertility, including follitropin alfa expressed in Chinese Hamster Ovary (CHO) cells and, more recently, follitropin delta expressed in the...
5.
6.
Piu F, Gauthier N, Olsson R, Currier E, Lund B, Croston G, et al.
Biochem Pharmacol
. 2005 Nov;
71(1-2):156-62.
PMID: 16303118
Drugs targeting retinoid receptors have been developed to treat a variety of therapeutic indications, but their success has been limited in part due to lack of selectivity. A novel functional...
7.
Croston G, Olsson R, Currier E, Burstein E, Weiner D, Nash N, et al.
J Med Chem
. 2002 Nov;
45(23):4950-3.
PMID: 12408704
A functional cell-based screen identified 3-(4-chlorophenyl)-3-(2-(dimethylamino)ethyl)isochroman-1-one hydrochloride (AC-7954, 1) as a nonpeptidic agonist of the urotensin-II receptor. Racemic 1 had an EC50 of 300 nM at the human UII receptor...
8.
Croston G
Trends Biotechnol
. 2002 Feb;
20(3):110-5.
PMID: 11841862
The availability of genomic information significantly increases the number of potential targets available for drug discovery, although the function of many targets and their relationship to disease is unknown. In...