Giuseppina Iachetta
Overview
Explore the profile of Giuseppina Iachetta including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
217
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Recent Articles
1.
Tentellino C, dAmora M, Melikov R, Iachetta G, Bruno G, Tantussi F, et al.
ACS Sens
. 2025 Feb;
10(2):1228-1236.
PMID: 39907650
neurotoxicology aims to assess and predict the side effects of exogenous chemicals toward the human brain. Among the exploited approaches, electrophysiological techniques stand out for the high spatiotemporal resolution and...
2.
Melikov R, Iachetta G, dAmora M, Melle G, Conti S, Tantussi F, et al.
Adv Mater
. 2025 Jan;
37(8):e2412697.
PMID: 39797475
Presently, the in vitro recording of intracellular neuronal signals on microelectrode arrays (MEAs) requires complex 3D nanostructures or invasive and approaches such as electroporation. Here, it is shown that laser...
3.
Interferometric Biosensor for High Sensitive Label-Free Recording of HiPS Cardiomyocytes Contraction
Boschi A, Iachetta G, Buonocore S, Hubarevich A, Hurtaud J, Moreddu R, et al.
Nano Lett
. 2024 May;
24(22):6451-6458.
PMID: 38776267
Heart disease remains a leading cause of global mortality, underscoring the need for advanced technologies to study cardiovascular diseases and develop effective treatments. We introduce an innovative interferometric biosensor for...
4.
Iachetta G, Melle G, Colistra N, Tantussi F, De Angelis F, Dipalo M
Arch Toxicol
. 2023 Jan;
97(2):509-522.
PMID: 36607357
The reliable identification of chronic cardiotoxic effects in in vitro screenings is fundamental for filtering out toxic molecular entities before in vivo animal experimentation and clinical trials. Present techniques such...
5.
Bruno G, Melle G, Barbaglia A, Iachetta G, Melikov R, Perrone M, et al.
Adv Sci (Weinh)
. 2021 Sep;
8(21):e2100627.
PMID: 34486241
Optical stimulation technologies are gaining great consideration in cardiology, neuroscience studies, and drug discovery pathways by providing control over cell activity with high spatio-temporal resolution. However, this high precision requires...
6.
Dipalo M, Rastogi S, Matino L, Garg R, Bliley J, Iachetta G, et al.
Sci Adv
. 2021 Apr;
7(15).
PMID: 33827809
Graphene with its unique electrical properties is a promising candidate for carbon-based biosensors such as microelectrodes and field effect transistors. Recently, graphene biosensors were successfully used for extracellular recording of...
7.
Iachetta G, Colistra N, Melle G, Deleye L, Tantussi F, De Angelis F, et al.
Toxicol Appl Pharmacol
. 2021 Mar;
418:115480.
PMID: 33689843
Drug-induced cardiotoxicity is a major barrier to drug development and a main cause of withdrawal of marketed drugs. Drugs can strongly alter the spontaneous functioning of the heart by interacting...
8.
Barbaglia A, Dipalo M, Melle G, Iachetta G, Deleye L, Hubarevich A, et al.
Adv Mater
. 2021 Jan;
33(7):e2004234.
PMID: 33410191
The electrophysiological recording of action potentials in human cells is a long-sought objective due to its pivotal importance in many disciplines. Among the developed techniques, invasiveness remains a common issue,...
9.
Iannelli F, Zotti A, Roca M, Grumetti L, Lombardi R, Moccia T, et al.
Front Cell Dev Biol
. 2020 Oct;
8:732.
PMID: 33015030
Recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC) is a devastating malignancy with a poor prognosis. The combination of cisplatin (CDDP) plus cetuximab (CX) is one of the standard...
10.
Melle G, Bruno G, Maccaferri N, Iachetta G, Colistra N, Barbaglia A, et al.
Front Bioeng Biotechnol
. 2020 Mar;
8:66.
PMID: 32133349
High quality attenuated intracellular action potentials from large cell networks can be recorded on multi-electrode arrays by means of 3D vertical nanopillars using electrical pulses. However, most of the techniques...