Giuseppe Vicidomini
Overview
Explore the profile of Giuseppe Vicidomini including associated specialties, affiliations and a list of published articles.
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Articles
64
Citations
1117
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Recent Articles
1.
Mariani D, Setti A, Castagnetti F, Vitiello E, Stufera Mecarelli L, Di Timoteo G, et al.
Nucleic Acids Res
. 2024 Nov;
52(21):13269-13289.
PMID: 39494508
Stress granules (SG) are part of a cellular protection mechanism where untranslated messenger RNAs and RNA-binding proteins are stored upon conditions of cellular stress. Compositional variations due to qualitative or...
2.
Fahim L, Marcus J, Powell N, Ralston Z, Walgamotte K, Perego E, et al.
J Cell Biol
. 2024 Oct;
224(1).
PMID: 39400294
Ribonucleoprotein (RNP) condensates partition RNA and protein into multiple liquid phases. The multiphasic feature of condensate-enriched components creates experimental challenges for distinguishing membraneless condensate functions from the surrounding dilute phase....
3.
Bucci A, Tortarolo G, Held M, Bega L, Perego E, Castagnetti F, et al.
Nat Commun
. 2024 Jul;
15(1):6188.
PMID: 39043637
Single-particle tracking techniques enable investigation of the complex functions and interactions of individual particles in biological environments. Many such techniques exist, each demonstrating trade-offs between spatiotemporal resolution, spatial and temporal...
4.
Di Timoteo G, Giuliani A, Setti A, Biagi M, Lisi M, Santini T, et al.
Nat Commun
. 2024 Jun;
15(1):5033.
PMID: 38866783
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease due to gradual motoneurons (MN) degeneration. Among the processes associated to ALS pathogenesis, there is the formation of cytoplasmic inclusions produced...
5.
Perego E, Zappone S, Castagnetti F, Mariani D, Vitiello E, Rupert J, et al.
Nat Commun
. 2023 Dec;
14(1):8224.
PMID: 38086853
Biomolecular condensates serve as membrane-less compartments within cells, concentrating proteins and nucleic acids to facilitate precise spatial and temporal orchestration of various biological processes. The diversity of these processes and...
6.
Sheppard C, Castello M, Tortarolo G, Zunino A, Slenders E, Bianchini P, et al.
J Opt Soc Am A Opt Image Sci Vis
. 2023 Sep;
40(8):1612-1619.
PMID: 37707118
We discuss the effects of image scanning microscopy using doughnut beam illumination on the properties of signal strength and integrated intensity. Doughnut beam illumination can give better optical sectioning and...
7.
Nepita I, Piazza S, Ruglioni M, Cristiani S, Bosurgi E, Salvadori T, et al.
Biology (Basel)
. 2023 Mar;
12(3).
PMID: 36979066
The genomes of metazoans are organized at multiple spatial scales, ranging from the double helix of DNA to whole chromosomes. The intermediate genomic scale of kilobases to megabases, which corresponds...
8.
Di Franco E, Costantino A, Cerutti E, DAmico M, Privitera A, Bianchini P, et al.
Sci Rep
. 2023 Feb;
13(1):2741.
PMID: 36792719
In point-scanning microscopy, optical sectioning is achieved using a small aperture placed in front of the detector, i.e. the detection pinhole, which rejects the out-of-focus background. The maximum level of...
9.
Sheppard C, Castello M, Tortarolo G, Zunino A, Slenders E, Bianchini P, et al.
J Opt Soc Am A Opt Image Sci Vis
. 2023 Jan;
40(1):138-148.
PMID: 36607082
The properties of signal strength and integrated intensity in a scanned imaging system are reviewed. These properties are especially applied to confocal imaging systems, including image scanning microscopy. The integrated...
10.
Tortarolo G, Zunino A, Fersini F, Castello M, Piazza S, Sheppard C, et al.
Nat Commun
. 2022 Dec;
13(1):7723.
PMID: 36513680
To date, the feasibility of super-resolution microscopy for imaging live and thick samples is still limited. Stimulated emission depletion (STED) microscopy requires high-intensity illumination to achieve sub-diffraction resolution, potentially introducing...