Giuseppe Scalabrino
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Explore the profile of Giuseppe Scalabrino including associated specialties, affiliations and a list of published articles.
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32
Citations
266
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Recent Articles
1.
Scalabrino G
Biomedicines
. 2022 Apr;
10(4).
PMID: 35453565
The pathogenesis of multiple sclerosis (MS) remains enigmatic and controversial. Myelin sheaths in the central nervous system (CNS) insulate axons and allow saltatory nerve conduction. MS brings about the destruction...
2.
Scalabrino G
Front Neurol
. 2021 Dec;
12:754270.
PMID: 34899572
Recent findings showing that epidermal growth factor (EGF) is significantly decreased in the cerebrospinal fluid (CSF) and spinal cord (SC) of living or deceased multiple sclerosis (MS) patients, and that...
3.
Scalabrino G
Cell Mol Neurobiol
. 2020 Nov;
42(4):891-916.
PMID: 33151415
This article reviews the wealth of papers dealing with the different effects of epidermal growth factor (EGF) on oligodendrocytes, astrocytes, neurons, and neural stem cells (NSCs). EGF induces the in...
4.
Nicoletti F, Mazzon E, Fagone P, Mangano K, Mammana S, Cavalli E, et al.
J Neuroimmunol
. 2019 May;
332:224-232.
PMID: 31100693
Epidermal growth factor (EGF) represents the prototype of the group I EGF family. The pleiotropic effects of the EGF have attracted attention to the possibility that it could be implicated...
5.
Are PrP(C)s involved in some human myelin diseases? Relating experimental studies to human pathology
Veber D, Scalabrino G
J Neurol Sci
. 2015 Oct;
359(1-2):396-403.
PMID: 26478128
We have experimentally demonstrated that cobalamin (Cbl) deficiency increases normal cellular prion (PrP(C)) levels in rat spinal cord (SC) and cerebrospinal fluid (CSF), and decreases PrP(C)-mRNA levels in rat SC....
6.
Scalabrino G, Veber D, Tredici G
Int J Biochem Cell Biol
. 2014 Sep;
55:232-41.
PMID: 25239885
Cobalamin (Cbl), epidermal growth factor (EGF), and prions (PrPs) are key molecules for myelin maintenance in the central and peripheral nervous systems. Cbl and EGF increase normal prion (PrP(C)) synthesis...
7.
Scalabrino G, Veber D
J Neurol
. 2013 Oct;
261(8):1451-60.
PMID: 24141733
Cobalamin (Cbl) deficiency causes an imbalance in some cytokines and growth factors in the central nervous system and peripheral nervous system (PNS) of the rat, and in the serum and...
8.
Scalabrino G, Veber D
Biochimie
. 2013 Jan;
95(5):1041-6.
PMID: 23328344
It is known that cobalamin (Cbl) deficiency damages myelin by increasing tumor necrosis factor (TNF)-α and decreasing epidermal growth factor (EGF) levels in rat central nervous system (CNS), and affects...
9.
Scalabrino G, Veber D
Clin Chem Lab Med
. 2012 Nov;
51(3):601-6.
PMID: 23183750
The pathogenesis of cobalamin (Cbl)-deficient (Cbl-D) neuropathy and the role of normal prions (PrPcs) in myelin maintenance are both subjects of debate. We have demonstrated that Cbl deficiency damages myelin...
10.
Scalabrino G, Veber D, Briani C, Milani S, Terralavoro A, Brenna S, et al.
J Clin Neurosci
. 2012 Nov;
20(1):134-8.
PMID: 23146213
We have previously demonstrated that the concentration of normal prion proteins (PrP(C)) is increased in the serum and cerebrospinal fluid (CSF) of rats deficient in vitamin B(12) (cobalamin, Cbl). In...