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Giuliana Castello Coatti

Explore the profile of Giuliana Castello Coatti including associated specialties, affiliations and a list of published articles. Areas
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Citations 70
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Recent Articles
1.
ODonnell C, Farelli J, Belaghzal H, Chen J, Beech L, Sullivan J, et al.
Nat Commun . 2025 Mar; 16(1):2517. PMID: 40082450
Pathogenic gene dysregulation can be attributed to chromatin state change that pre-transcriptionally regulates expression. Recent breakthroughs elucidating the rules governing this DNA control layer, an epigenetic code, unlock a modality...
2.
Baranoski A, Semprebon S, Biazi B, Zanetti T, Corveloni A, Areal Marques L, et al.
J Toxicol Environ Health A . 2024 Jan; 87(7):294-309. PMID: 38279841
Piperlongumine (PLN) is a biologically active alkaloid/amide derived from , with known promising anticancer activity. The aim of this study was to compare the antiproliferative activity of PLN in human...
3.
Rondina D, de Lima L, da Silva M, Zanetti T, Felicidade I, Areal Marques L, et al.
Toxicol In Vitro . 2022 Sep; 85:105474. PMID: 36122806
Zerumbone (ZER) is a phytochemical with antioxidant and antiproliferative properties. This study evaluated the cytoxicity of ZER combined with chemotherapeutic agents and the expression of mRNA genes related to cell...
4.
de Lima L, da Silva M, Concato V, Rondina D, Zanetti T, Felicidade I, et al.
J Toxicol Environ Health A . 2022 Aug; 85(21):896-911. PMID: 35950849
Fluopsin C is an antibiotic compound derived from secondary metabolism of different microorganisms, which possesses antitumor, antibacterial, and antifungal activity. Related to fluopsin C antiproliferative activity, the aim of this...
5.
Zanetti T, Biazi B, Castello Coatti G, Baranoski A, Areal Marques L, Corveloni A, et al.
Chem Biol Interact . 2021 Feb; 338:109410. PMID: 33582110
Curcumin (Cur), is a pigment with antiproliferative activity but has some pharmacokinetic limitations, which led researchers to look for more effective structure analogs. This work investigated the effects of Cur...
6.
Vaz Crippa G, Zanetti T, Biazi B, Baranoski A, Areal Marques L, Castello Coatti G, et al.
Environ Toxicol Pharmacol . 2020 Jan; 75:103328. PMID: 32000057
Studies that evaluated the mechanisms of action of Plumbagin (PLB) and its toxicity may contribute to future therapeutic applications of this compound. We investigate biomarker important in the mechanisms of...
7.
Zanetti T, Biazi B, Castello Coatti G, Baranoski A, Areal Marques L, Corveloni A, et al.
Toxicol In Vitro . 2019 Sep; 61:104643. PMID: 31513842
Dimethoxycurcumin (DiMC), a synthetic analog of curcumin, was shown to have antiproliferative activity in human tumor cell lines. Therefore, we investigated its cytotoxic, antiproliferative, genotoxic, and apoptotic effect and correlated...
8.
Mancilla I, Castello Coatti G, Biazi B, Zanetti T, Baranoski A, Areal Marques L, et al.
Mol Biol Rep . 2019 Aug; 46(6):6071-6078. PMID: 31456160
Plumbagin (PLB) is a phytochemical being used for centuries in traditional medicines. Recently, its capacity to inhibit the development of human tumors has been observed, through the induction of apoptosis,...
9.
Castello Coatti G, Cavacana N, Zatz M
Adv Exp Med Biol . 2019 Jun; 1147:137-146. PMID: 31147876
In amyotrophic lateral sclerosis (ALS), motor neurons die selectively. Therefore, initial symptoms that include fasciculation, spasticity, muscle atrophy, and weakness emerge following axons retraction and consequent muscles' denervation. Patients lose...
10.
Zanetti T, Biazi B, Baranoski A, DEpiro G, Corveloni A, Semprebon S, et al.
J Trace Elem Med Biol . 2018 Sep; 50:209-215. PMID: 30262281
Oxidative stress (OS) is involved in the onset of various pathological processes, and sodium selenite (NaSeO) is known to have antioxidant activity. This study evaluated the cellular response of human...