Giulia Refolo
Overview
Explore the profile of Giulia Refolo including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
244
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Recent Articles
1.
Di Rienzo M, Romagnoli A, Refolo G, Vescovo T, Ciccosanti F, Zuchegna C, et al.
Autophagy
. 2024 Aug;
20(12):2602-2615.
PMID: 39113560
Aging is a gradual and irreversible physiological process that significantly increases the risks of developing a variety of pathologies, including neurodegenerative, cardiovascular, metabolic, musculoskeletal, and immune system diseases. Mitochondria are...
2.
Di Rienzo M, Romagnoli A, Ciccosanti F, Refolo G, Consalvi V, Arena G, et al.
Autophagy
. 2021 Nov;
18(8):1752-1762.
PMID: 34798798
PINK1 accumulation at the outer mitochondrial membrane (OMM) is a key event required to signal depolarized mitochondria to the autophagy machinery. How this early step is, in turn, modulated by...
3.
Ciccosanti F, Corazzari M, Casetti R, Amendola A, Collalto D, Refolo G, et al.
Cells
. 2021 Jun;
10(5).
PMID: 34069225
Autophagy is a lysosomal-dependent degradative mechanism essential in maintaining cellular homeostasis, but it is also considered an ancient form of innate eukaryotic fighting against invading microorganisms. Mounting evidence has shown...
4.
Ciccosanti F, Di Rienzo M, Romagnoli A, Colavita F, Refolo G, Castilletti C, et al.
Antiviral Res
. 2021 Mar;
190:105064.
PMID: 33781803
COVID-19 is currently a highly pressing health threat and therapeutic strategies to mitigate the infection impact are urgently needed. Characterization of the SARS-CoV-2 interactome in infected cells may represent a...
5.
Bordoni V, Tartaglia E, Refolo G, Sacchi A, Grassi G, Antinori A, et al.
Front Cell Infect Microbiol
. 2020 Aug;
10:362.
PMID: 32850472
Chronic HIV infection accelerates immune aging and is associated with abnormal hemato-lymphopoiesis, but the relationship between HIV-induced aging and Hematopoietic Progenitor Cells (HPC) function is not well-defined. In the context...
6.
Refolo G, Vescovo T, Piacentini M, Fimia G, Ciccosanti F
Front Cell Dev Biol
. 2020 Mar;
8:8.
PMID: 32117959
In the last years, proteomics has represented a valuable approach to elucidate key aspects in the regulation of type I/III interferons (IFNs) and autophagy, two main processes involved in the...
7.
Vescovo T, Refolo G, Ciancio Manuelli M, Tisone G, Piacentini M, Fimia G
Front Pharmacol
. 2019 Jul;
10:718.
PMID: 31316383
Statins efficiently inhibit cholesterol synthesis by blocking 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase in the mevalonate pathway. However, the effect of statins on intracellular cholesterol is partially counterbalanced by a consequent increased uptake...
8.
DEletto M, Rossin F, Occhigrossi L, Farrace M, Faccenda D, Desai R, et al.
Cell Rep
. 2018 Dec;
25(13):3573-3581.e4.
PMID: 30590033
Transglutaminase type 2 (TG2) is a multifunctional enzyme that plays a key role in mitochondria homeostasis under stressful cellular conditions. TG2 interactome analysis reveals an enzyme interaction with GRP75 (glucose-regulated...
9.
Refolo G, Ciccosanti F, Di Rienzo M, Basulto Perdomo A, Romani M, Alonzi T, et al.
Hepatology
. 2018 Aug;
69(1):34-50.
PMID: 30070380
Hepatitis C virus (HCV) is highly efficient in establishing a chronic infection, having evolved multiple strategies to suppress the host antiviral responses. The HCV nonstructural 5A (NS5A) protein, in addition...
10.
Mancone C, Grimaldi A, Refolo G, Abbate I, Rozera G, Benelli D, et al.
Proteome Sci
. 2017 Aug;
15:18.
PMID: 28785172
Background: Changes in iron metabolism frequently accompany HIV-1 infection. However, while many clinical and in vitro studies report iron overload exacerbates the development of infection, many others have found no...