Giovanna Baron
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Explore the profile of Giovanna Baron including associated specialties, affiliations and a list of published articles.
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44
Citations
566
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Recent Articles
1.
Della Vedova L, Baron G, Morazzoni P, Aldini G, Gado F
Pharmaceuticals (Basel)
. 2025 Feb;
18(2).
PMID: 40005954
: Cellular senescence is a biological process with a dual role in organismal health. While transient senescence supports tissue repair and acts as a tumor-suppressive mechanism, the chronic accumulation of...
2.
Novel Orthosteric/Allosteric Ligands of Cannabinoid Receptors: An Unexpected Pharmacological Profile
Ferrisi R, Polini B, Smolyakova A, Migone C, Giammattei G, Banti M, et al.
J Med Chem
. 2025 Jan;
68(2):1280-1299.
PMID: 39749716
The design of dualsteric/bitopic receptor ligands as compounds capable of simultaneously interacting with both the orthosteric and an allosteric binding site has gained importance to achieve enhanced receptor specificity and...
3.
Della Vedova L, Husain I, Wang Y, Kothapalli H, Gado F, Baron G, et al.
Arch Pharm (Weinheim)
. 2024 Nov;
358(1):e2400575.
PMID: 39526505
5-(3',4'-Dihydroxyphenyl)-γ-valerolactone (VL) is a bioactive metabolite resulting from the gut microbial metabolism of proanthocyanidins and flavonoids, known for its health-promoting effects, including antidiabetic and anti-inflammatory activities. Although VL has been...
4.
Mazzola G, Rondanelli M, Baron G, Zupo R, Castellana F, Clodoveo M, et al.
Foods
. 2024 Nov;
13(21).
PMID: 39517207
This systematic review investigates the potential of bergamot, a polyphenol-rich citrus fruit, in improving osteosarcopenic obesity, a condition characterized by the simultaneous presence of osteoporosis, obesity, and sarcopenia. Bergamot extracts...
5.
DAmato A, Altomare A, Gilardoni E, Baron G, Carini M, Melloni E, et al.
Redox Biol
. 2024 Oct;
77:103374.
PMID: 39393288
The aim of the work was to study a dose-dependent effect of inhaled carnosine (10, 50 or 100 mg/kg/day) in mice exposed to cigarette smoke as a model of chronic...
6.
Altomare A, Baron G, Cambiaghi G, Ferrario G, Zoanni B, Della Vedova L, et al.
Molecules
. 2024 Jun;
29(11).
PMID: 38893578
Background: The viral main protease (M) of SARS-CoV-2 has been recently proposed as a key target to inhibit virus replication in the host. Therefore, molecules that can bind the catalytic...
7.
Caroli C, Baron G, Cappellucci G, Brighenti V, Della Vedova L, Fraulini F, et al.
Heliyon
. 2024 May;
10(9):e30291.
PMID: 38737258
Policosanols (PCs) are bioactive compounds extracted from different natural waxes. In this work, the purification, characterization and assessment of the antioxidant and anti-inflammatory activity was carried out on PCs from...
8.
Artasensi A, Mazzotta S, Baron G, Aldini G, Fumagalli L
RSC Adv
. 2024 Feb;
14(9):6410-6415.
PMID: 38380241
Deuterated proanthocyanidin metabolite 5-(3',4'-dihydroxyphenyl)-γ-valerolactone has been successfully produced. This metabolite is responsible for several proanthocyanidin protective effects in the field of cancer chemoprevention, skin wrinkle-prevention, and antimicrobials. The synthetic approach...
9.
Della Vedova L, Gado F, Vieira T, Grandini N, Palacio T, Siqueira J, et al.
Molecules
. 2023 Apr;
28(7).
PMID: 37049725
The present paper reports a sustainable raw material obtained from the by-products derived from the industrial production of bergamot ( × Risso & Poiteau) essential oils. The procedure to obtain...
10.
Nakandakare-Maia E, Siqueira J, Ferron A, Vieira T, Palacio T, Grandini N, et al.
Mol Cell Endocrinol
. 2023 Mar;
566-567:111908.
PMID: 36868453
Low-grade chronic inflammation in obesity is associated with leptin resistance. In order to alleviate this pathological condition, bioactive compounds capable of attenuating oxidative stress and inflammation have been researched, and...